Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| A | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| B | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1392 |
| Chain | Residue |
| A | GLY197 |
| A | HOH2430 |
| A | GLY198 |
| A | THR199 |
| A | ILE221 |
| A | ARG222 |
| A | ARG224 |
| A | HOH2230 |
| A | HOH2428 |
| A | HOH2429 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1393 |
| Chain | Residue |
| A | ARG285 |
| A | SER309 |
| A | HOH2431 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1394 |
| Chain | Residue |
| A | ARG285 |
| A | HOH2432 |
| A | HOH2433 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1395 |
| Chain | Residue |
| A | GLN151 |
| A | HOH2119 |
| A | HOH2435 |
| A | HOH2436 |
| A | HOH2437 |
| A | HOH2438 |
| A | HOH2439 |
| B | LYS61 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1396 |
| Chain | Residue |
| A | SER200 |
| A | ALA201 |
| A | LYS381 |
| A | HOH2440 |
| A | HOH2443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1397 |
| Chain | Residue |
| A | ASN68 |
| A | PRO69 |
| A | SER70 |
| A | HOH2053 |
| A | HOH2444 |
| A | HOH2445 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1398 |
| Chain | Residue |
| A | GLN33 |
| A | HIS34 |
| A | LYS85 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1391 |
| Chain | Residue |
| B | GLY197 |
| B | GLY198 |
| B | THR199 |
| B | VAL220 |
| B | ILE221 |
| B | ARG222 |
| B | ARG224 |
| B | HOH2270 |
| B | HOH2302 |
| B | HOH2452 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1392 |
| Chain | Residue |
| B | PRO69 |
| B | ASN172 |
| B | ALA201 |
| B | LYS381 |
| B | HOH2251 |
| B | HOH2444 |
| B | HOH2454 |
| B | HOH2455 |
| B | HOH2456 |
| B | HOH2457 |
| B | HOH2458 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1393 |
| Chain | Residue |
| B | GLN33 |
| B | HIS34 |
| B | LYS85 |
| B | HOH2459 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1394 |
| Chain | Residue |
| B | THR162 |
| B | ILE163 |
| B | HOH2408 |
| B | HOH2461 |
| B | HOH2463 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1395 |
| Chain | Residue |
| B | HIS182 |
| B | LEU326 |
| B | HOH2367 |
| B | HOH2464 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1396 |
| Chain | Residue |
| B | ARG285 |
| B | SER309 |
| B | HOH2465 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1387 |
| Chain | Residue |
| A | PHE321 |
| A | TRP322 |
| A | GLU325 |
| A | HOH2209 |
| A | HOH2418 |
| B | TYR311 |
| B | ILE312 |
| B | ASN315 |
| B | HOH2346 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1388 |
| Chain | Residue |
| A | VAL127 |
| A | SER170 |
| A | THR324 |
| A | LEU327 |
| A | LYS334 |
| A | HOH2419 |
| A | HOH2420 |
| A | HOH2421 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1389 |
| Chain | Residue |
| A | GLU267 |
| A | LEU287 |
| A | ASN288 |
| A | ASN289 |
| A | LYS314 |
| A | HOH2422 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1390 |
| Chain | Residue |
| A | LEU326 |
| A | ASN330 |
| A | HOH2423 |
| A | HOH2424 |
| A | HIS182 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1391 |
| Chain | Residue |
| A | LYS204 |
| A | ALA353 |
| A | LYS354 |
| A | HOH2425 |
| A | HOH2426 |
| A | HOH2427 |
| site_id | CC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 1387 |
| Chain | Residue |
| A | TYR311 |
| A | ILE312 |
| A | ASN315 |
| A | HOH2323 |
| B | GLY320 |
| B | PHE321 |
| B | TRP322 |
| B | GLU325 |
| B | HOH2238 |
| B | HOH2450 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1388 |
| Chain | Residue |
| B | THR32 |
| B | THR91 |
| B | THR92 |
| B | GLU93 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1389 |
| Chain | Residue |
| B | ASN100 |
| B | PRO124 |
| B | SER125 |
| B | HIS126 |
| B | SER170 |
| B | LYS334 |
| B | HOH2226 |
| B | HOH2451 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1390 |
| Chain | Residue |
| B | GLU267 |
| B | ASN288 |
| B | ASN289 |
| B | LYS314 |
| B | HOH2317 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"25867044","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12614607","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12890667","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| A | TYR79 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| B | TYR79 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| A | ASN73 | |
| A | SER70 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| B | ASN73 | |
| B | SER70 | |
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| A | TYR79 | electrostatic stabiliser, increase electrophilicity |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| B | TYR79 | electrostatic stabiliser, increase electrophilicity |
