1GQ2
Malic Enzyme from Pigeon Liver
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004470 | molecular_function | malic enzyme activity |
| A | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006108 | biological_process | malate metabolic process |
| A | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004470 | molecular_function | malic enzyme activity |
| B | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006108 | biological_process | malate metabolic process |
| B | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0004470 | molecular_function | malic enzyme activity |
| C | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0006108 | biological_process | malate metabolic process |
| C | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051287 | molecular_function | NAD binding |
| D | 0004470 | molecular_function | malic enzyme activity |
| D | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0006108 | biological_process | malate metabolic process |
| D | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051287 | molecular_function | NAD binding |
| E | 0004470 | molecular_function | malic enzyme activity |
| E | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0006108 | biological_process | malate metabolic process |
| E | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0051287 | molecular_function | NAD binding |
| F | 0004470 | molecular_function | malic enzyme activity |
| F | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0006108 | biological_process | malate metabolic process |
| F | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0051287 | molecular_function | NAD binding |
| G | 0004470 | molecular_function | malic enzyme activity |
| G | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0006108 | biological_process | malate metabolic process |
| G | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051287 | molecular_function | NAD binding |
| H | 0004470 | molecular_function | malic enzyme activity |
| H | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0006108 | biological_process | malate metabolic process |
| H | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051287 | molecular_function | NAD binding |
| I | 0004470 | molecular_function | malic enzyme activity |
| I | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005739 | cellular_component | mitochondrion |
| I | 0006108 | biological_process | malate metabolic process |
| I | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0051287 | molecular_function | NAD binding |
| J | 0004470 | molecular_function | malic enzyme activity |
| J | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0006108 | biological_process | malate metabolic process |
| J | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0051287 | molecular_function | NAD binding |
| K | 0004470 | molecular_function | malic enzyme activity |
| K | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005739 | cellular_component | mitochondrion |
| K | 0006108 | biological_process | malate metabolic process |
| K | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0051287 | molecular_function | NAD binding |
| L | 0004470 | molecular_function | malic enzyme activity |
| L | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005739 | cellular_component | mitochondrion |
| L | 0006108 | biological_process | malate metabolic process |
| L | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| L | 0016491 | molecular_function | oxidoreductase activity |
| L | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0051287 | molecular_function | NAD binding |
| M | 0004470 | molecular_function | malic enzyme activity |
| M | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0005739 | cellular_component | mitochondrion |
| M | 0006108 | biological_process | malate metabolic process |
| M | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| M | 0016491 | molecular_function | oxidoreductase activity |
| M | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| M | 0046872 | molecular_function | metal ion binding |
| M | 0051287 | molecular_function | NAD binding |
| N | 0004470 | molecular_function | malic enzyme activity |
| N | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0005739 | cellular_component | mitochondrion |
| N | 0006108 | biological_process | malate metabolic process |
| N | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| N | 0016491 | molecular_function | oxidoreductase activity |
| N | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| N | 0046872 | molecular_function | metal ion binding |
| N | 0051287 | molecular_function | NAD binding |
| O | 0004470 | molecular_function | malic enzyme activity |
| O | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0005739 | cellular_component | mitochondrion |
| O | 0006108 | biological_process | malate metabolic process |
| O | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| O | 0016491 | molecular_function | oxidoreductase activity |
| O | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| O | 0046872 | molecular_function | metal ion binding |
| O | 0051287 | molecular_function | NAD binding |
| P | 0004470 | molecular_function | malic enzyme activity |
| P | 0004473 | molecular_function | malate dehydrogenase (decarboxylating) (NADP+) activity |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0005739 | cellular_component | mitochondrion |
| P | 0006108 | biological_process | malate metabolic process |
| P | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| P | 0016491 | molecular_function | oxidoreductase activity |
| P | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| P | 0046872 | molecular_function | metal ion binding |
| P | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL A1583 |
| Chain | Residue |
| A | ARG165 |
| A | NAP1581 |
| A | MN1584 |
| A | HOH2035 |
| A | LEU167 |
| A | LYS183 |
| A | GLU255 |
| A | ASP256 |
| A | ASP279 |
| A | ASN421 |
| A | ASN466 |
| A | ASN467 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A1584 |
| Chain | Residue |
| A | LYS183 |
| A | GLU255 |
| A | ASP256 |
| A | ASP279 |
| A | OXL1583 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL B1582 |
| Chain | Residue |
| B | TYR112 |
| B | ARG165 |
| B | LEU167 |
| B | LYS183 |
| B | GLU255 |
| B | ASP256 |
| B | ASP279 |
| B | ASN421 |
| B | ASN466 |
| B | ASN467 |
| B | NAP1581 |
| B | MN1583 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B1583 |
| Chain | Residue |
| B | ARG165 |
| B | LYS183 |
| B | GLU255 |
| B | ASP256 |
| B | ASP279 |
| B | OXL1582 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B1584 |
| Chain | Residue |
| B | MSE38 |
| B | GLN64 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OXL C1582 |
| Chain | Residue |
| C | ARG165 |
| C | LEU167 |
| C | LYS183 |
| C | GLU255 |
| C | ASP256 |
| C | ASP279 |
| C | ASN421 |
| C | ASN466 |
| C | ASN467 |
| C | NAP1581 |
| C | MN1583 |
| C | HOH2076 |
| C | HOH2077 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C1583 |
| Chain | Residue |
| C | GLU255 |
| C | ASP256 |
| C | ASP279 |
| C | OXL1582 |
| C | HOH2077 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C1584 |
| Chain | Residue |
| C | PHE72 |
| C | GLU73 |
| C | LEU75 |
| C | ARG81 |
| C | HOH2014 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C1585 |
| Chain | Residue |
| C | TRP342 |
| C | MSE343 |
| C | ILE350 |
| C | PHE365 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA C1586 |
| Chain | Residue |
| C | ASN271 |
| C | HIS485 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA C1587 |
| Chain | Residue |
| C | TYR82 |
| C | MSE86 |
| C | TYR123 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C1588 |
| Chain | Residue |
| C | ASP78 |
| C | LEU79 |
| C | LEU118 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C1589 |
| Chain | Residue |
| C | GLN121 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C1590 |
| Chain | Residue |
| C | GLU105 |
| C | ARG511 |
| C | LEU516 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C1591 |
| Chain | Residue |
| C | GLN61 |
| C | ASP561 |
| C | TYR562 |
| site_id | BC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE OXL D1582 |
| Chain | Residue |
| D | TYR112 |
| D | ARG165 |
| D | LEU167 |
| D | LYS183 |
| D | GLU255 |
| D | ASP256 |
| D | ASP279 |
| D | ASN421 |
| D | ASN466 |
| D | ASN467 |
| D | NAP1581 |
| D | MN1583 |
| D | NA1584 |
| D | HOH2049 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN D1583 |
| Chain | Residue |
| D | GLU255 |
| D | ASP256 |
| D | ASP279 |
| D | OXL1582 |
| D | HOH2049 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA D1584 |
| Chain | Residue |
| D | THR113 |
| D | ASN421 |
| D | ASN466 |
| D | OXL1582 |
| D | TYR112 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA D1585 |
| Chain | Residue |
| D | MSE38 |
| D | GLN64 |
| site_id | CC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL E1582 |
| Chain | Residue |
| E | ARG165 |
| E | LEU167 |
| E | LYS183 |
| E | GLU255 |
| E | ASP256 |
| E | ASP279 |
| E | ASN421 |
| E | ASN466 |
| E | ASN467 |
| E | NAP1581 |
| E | MN1583 |
| E | HOH2057 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN E1583 |
| Chain | Residue |
| E | GLU255 |
| E | ASP256 |
| E | ASP279 |
| E | OXL1582 |
| E | HOH2058 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL E1584 |
| Chain | Residue |
| E | ASP162 |
| E | GLU164 |
| E | ALA258 |
| E | ASN261 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E1585 |
| Chain | Residue |
| E | GLN61 |
| E | TYR562 |
| E | HOH2009 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL E1586 |
| Chain | Residue |
| E | TYR112 |
| E | LYS183 |
| site_id | CC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL F1582 |
| Chain | Residue |
| F | ARG165 |
| F | LEU167 |
| F | LYS183 |
| F | ASP256 |
| F | ASP279 |
| F | ASN421 |
| F | ASN466 |
| F | ASN467 |
| F | NAP1581 |
| F | MN1583 |
| F | HOH2077 |
| F | HOH2078 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN F1583 |
| Chain | Residue |
| F | GLU255 |
| F | ASP256 |
| F | ASP279 |
| F | OXL1582 |
| F | HOH2078 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA F1584 |
| Chain | Residue |
| F | LEU483 |
| F | ASN537 |
| F | THR539 |
| F | HOH2072 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA F1585 |
| Chain | Residue |
| F | ASP90 |
| F | ARG129 |
| F | ARG131 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F1586 |
| Chain | Residue |
| F | TYR112 |
| F | LEU167 |
| F | LYS183 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F1587 |
| Chain | Residue |
| F | GLY37 |
| F | MSE38 |
| F | GLN64 |
| site_id | DC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL G1582 |
| Chain | Residue |
| G | ARG165 |
| G | LEU167 |
| G | LYS183 |
| G | GLU255 |
| G | ASP256 |
| G | ASP279 |
| G | ASN421 |
| G | ASN466 |
| G | ASN467 |
| G | NAP1581 |
| G | MN1583 |
| G | HOH2065 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN G1583 |
| Chain | Residue |
| G | GLU255 |
| G | ASP256 |
| G | ASP279 |
| G | OXL1582 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA G1584 |
| Chain | Residue |
| G | LEU29 |
| G | ARG30 |
| G | ASP31 |
| G | PRO32 |
| G | ARG91 |
| H | ARG129 |
| site_id | DC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL G1585 |
| Chain | Residue |
| G | TYR558 |
| G | SER559 |
| site_id | DC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OXL H1582 |
| Chain | Residue |
| H | ARG165 |
| H | LYS183 |
| H | GLU255 |
| H | ASP256 |
| H | ASP279 |
| H | ASN421 |
| H | ASN466 |
| H | ASN467 |
| H | NAP1581 |
| H | MN1583 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN H1583 |
| Chain | Residue |
| H | LYS183 |
| H | GLU255 |
| H | ASP256 |
| H | ASP279 |
| H | OXL1582 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA H1584 |
| Chain | Residue |
| H | MSE108 |
| H | THR113 |
| H | PRO448 |
| H | GLN464 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA H1585 |
| Chain | Residue |
| H | GLY117 |
| H | LEU118 |
| H | GLN121 |
| H | LEU169 |
| H | NA1587 |
| H | HOH2018 |
| site_id | EC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA H1586 |
| Chain | Residue |
| H | GLU330 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA H1587 |
| Chain | Residue |
| H | SER424 |
| H | NA1585 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA H1588 |
| Chain | Residue |
| H | GLN310 |
| H | ALA393 |
| H | ALA394 |
| H | ILE395 |
| H | GLU427 |
| site_id | EC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL H1589 |
| Chain | Residue |
| H | GLN405 |
| H | ALA408 |
| H | ALA409 |
| site_id | EC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OXL I1582 |
| Chain | Residue |
| I | ARG165 |
| I | LEU167 |
| I | LYS183 |
| I | GLU255 |
| I | ASP256 |
| I | ASP279 |
| I | ASN421 |
| I | ASN467 |
| I | NAP1581 |
| I | MN1583 |
| I | HOH2080 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN I1583 |
| Chain | Residue |
| I | LYS183 |
| I | GLU255 |
| I | ASP256 |
| I | ASP279 |
| I | OXL1582 |
| site_id | EC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA I1584 |
| Chain | Residue |
| I | TRP342 |
| I | MSE343 |
| I | ILE350 |
| I | PHE365 |
| site_id | FC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA I1585 |
| Chain | Residue |
| I | GLU330 |
| M | ASP304 |
| M | HIS305 |
| M | THR306 |
| site_id | FC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL I1586 |
| Chain | Residue |
| I | ASP256 |
| I | PHE257 |
| I | ASN277 |
| I | ASP279 |
| I | GLU314 |
| site_id | FC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL I1587 |
| Chain | Residue |
| I | ASP450 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL I1588 |
| Chain | Residue |
| I | ARG270 |
| I | ASN271 |
| I | ILE486 |
| I | GLY487 |
| site_id | FC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL I1589 |
| Chain | Residue |
| I | ARG413 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL I1590 |
| Chain | Residue |
| I | ARG270 |
| I | GLY487 |
| I | ASP488 |
| site_id | FC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL J1582 |
| Chain | Residue |
| J | TYR112 |
| J | ARG165 |
| J | LEU167 |
| J | LYS183 |
| J | GLU255 |
| J | ASP256 |
| J | ASP279 |
| J | ASN421 |
| J | ASN466 |
| J | ASN467 |
| J | NAP1581 |
| J | MN1583 |
| site_id | FC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN J1583 |
| Chain | Residue |
| J | GLU255 |
| J | ASP256 |
| J | ASP279 |
| J | OXL1582 |
| J | HOH2063 |
| site_id | FC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA J1584 |
| Chain | Residue |
| J | PHE443 |
| J | GLY463 |
| J | GLY510 |
| J | ARG511 |
| J | LEU512 |
| site_id | GC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA J1585 |
| Chain | Residue |
| J | MSE108 |
| J | THR113 |
| J | GLN464 |
| site_id | GC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL J1586 |
| Chain | Residue |
| I | ARG129 |
| J | SER87 |
| J | ARG91 |
| site_id | GC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL J1587 |
| Chain | Residue |
| I | ARG128 |
| I | HOH2013 |
| site_id | GC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OXL K1582 |
| Chain | Residue |
| K | ARG165 |
| K | LEU167 |
| K | LYS183 |
| K | GLU255 |
| K | ASP256 |
| K | ASP279 |
| K | ASN421 |
| K | ASN466 |
| K | ASN467 |
| K | NAP1581 |
| K | MN1583 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN K1583 |
| Chain | Residue |
| K | GLU255 |
| K | ASP256 |
| K | ASP279 |
| K | OXL1582 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA K1584 |
| Chain | Residue |
| K | TYR218 |
| K | GLY220 |
| K | ARG222 |
| L | CYS57 |
| site_id | GC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL K1585 |
| Chain | Residue |
| K | ARG270 |
| site_id | GC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OXL L1582 |
| Chain | Residue |
| L | ARG165 |
| L | LEU167 |
| L | LYS183 |
| L | GLU255 |
| L | ASP256 |
| L | ASP279 |
| L | ASN421 |
| L | ASN467 |
| L | NAP1581 |
| L | MN1583 |
| L | HOH2075 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN L1583 |
| Chain | Residue |
| L | GLU255 |
| L | ASP256 |
| L | ASP279 |
| L | OXL1582 |
| L | HOH2075 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA L1584 |
| Chain | Residue |
| L | TYR469 |
| L | PRO472 |
| L | GLY473 |
| L | SER523 |
| site_id | HC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL L1585 |
| Chain | Residue |
| L | ASN506 |
| L | PRO515 |
| site_id | HC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OXL M1582 |
| Chain | Residue |
| M | TYR112 |
| M | ARG165 |
| M | LEU167 |
| M | LYS183 |
| M | GLU255 |
| M | ASP256 |
| M | ASP279 |
| M | ASN421 |
| M | ASN466 |
| M | ASN467 |
| M | NAP1581 |
| M | MN1583 |
| M | HOH2018 |
| site_id | HC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN M1583 |
| Chain | Residue |
| M | GLU255 |
| M | ASP256 |
| M | ASP279 |
| M | OXL1582 |
| M | HOH2081 |
| site_id | HC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA M1584 |
| Chain | Residue |
| M | GLU330 |
| site_id | HC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA M1585 |
| Chain | Residue |
| M | LEU292 |
| site_id | HC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA M1586 |
| Chain | Residue |
| M | TYR469 |
| M | GLY473 |
| M | SER523 |
| M | ILE526 |
| site_id | HC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA M1587 |
| Chain | Residue |
| M | THR298 |
| M | THR387 |
| M | ARG413 |
| M | ILE415 |
| site_id | HC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA M1588 |
| Chain | Residue |
| M | ASP204 |
| M | GLY206 |
| M | THR207 |
| M | TYR218 |
| M | LEU221 |
| site_id | IC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA M1589 |
| Chain | Residue |
| M | ARG129 |
| N | LEU29 |
| site_id | IC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL M1590 |
| Chain | Residue |
| M | MSE38 |
| M | GLN64 |
| site_id | IC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL M1591 |
| Chain | Residue |
| M | HIS122 |
| M | GLY124 |
| M | LEU125 |
| M | TYR175 |
| M | LEU217 |
| site_id | IC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL M1592 |
| Chain | Residue |
| M | HIS485 |
| M | HOH2035 |
| P | PRO544 |
| site_id | IC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OXL N1582 |
| Chain | Residue |
| N | ARG165 |
| N | LEU167 |
| N | LYS183 |
| N | GLU255 |
| N | ASP256 |
| N | ASP279 |
| N | ASN421 |
| N | ASN466 |
| N | ASN467 |
| N | NAP1581 |
| N | MN1583 |
| site_id | IC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN N1583 |
| Chain | Residue |
| N | GLU255 |
| N | ASP256 |
| N | ASP279 |
| N | OXL1582 |
| N | HOH2071 |
| site_id | IC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA N1584 |
| Chain | Residue |
| N | ASP103 |
| N | ILE104 |
| N | GLU105 |
| site_id | IC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL N1585 |
| Chain | Residue |
| N | MSE38 |
| N | GLN64 |
| site_id | IC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL N1586 |
| Chain | Residue |
| N | THR518 |
| N | GLN520 |
| N | GLN521 |
| site_id | JC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OXL O1582 |
| Chain | Residue |
| O | ARG165 |
| O | LEU167 |
| O | LYS183 |
| O | GLU255 |
| O | ASP256 |
| O | ASP279 |
| O | ASN421 |
| O | ASN467 |
| O | NAP1581 |
| O | MN1583 |
| site_id | JC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN O1583 |
| Chain | Residue |
| O | GLU255 |
| O | ASP256 |
| O | ASP279 |
| O | OXL1582 |
| O | HOH2078 |
| site_id | JC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA O1584 |
| Chain | Residue |
| O | ASP256 |
| O | PHE257 |
| O | ASN277 |
| O | ASP279 |
| O | GLU314 |
| site_id | JC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA O1585 |
| Chain | Residue |
| O | GLY318 |
| O | ASN321 |
| O | ASP488 |
| site_id | JC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA O1586 |
| Chain | Residue |
| O | TYR82 |
| O | VAL116 |
| O | GLY178 |
| O | GLY182 |
| site_id | JC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA O1587 |
| Chain | Residue |
| O | ARG165 |
| O | LEU167 |
| O | GLY168 |
| O | LEU169 |
| O | GLY170 |
| site_id | JC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL O1588 |
| Chain | Residue |
| O | ASN506 |
| O | PRO515 |
| site_id | JC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL O1589 |
| Chain | Residue |
| O | ASP162 |
| O | GLU164 |
| O | ALA258 |
| O | ASN261 |
| site_id | JC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL O1590 |
| Chain | Residue |
| O | PRO422 |
| O | THR423 |
| O | SER424 |
| site_id | KC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL O1591 |
| Chain | Residue |
| O | HIS122 |
| O | GLY124 |
| O | LEU125 |
| O | TYR175 |
| O | LEU217 |
| O | HOH2030 |
| site_id | KC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OXL P1582 |
| Chain | Residue |
| P | ARG165 |
| P | LEU167 |
| P | LYS183 |
| P | GLU255 |
| P | ASP279 |
| P | ASN421 |
| P | ASN466 |
| P | ASN467 |
| P | NAP1581 |
| P | MN1583 |
| site_id | KC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN P1583 |
| Chain | Residue |
| P | GLU255 |
| P | ASP256 |
| P | ASP279 |
| P | OXL1582 |
| site_id | KC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA P1584 |
| Chain | Residue |
| P | PHE565 |
| site_id | KC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA P1585 |
| Chain | Residue |
| P | ALA418 |
| P | SER420 |
| P | ASN421 |
| P | ALA426 |
| P | GLY446 |
| P | SER447 |
| site_id | KC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA P1586 |
| Chain | Residue |
| P | ARG413 |
| P | GLY439 |
| P | ARG440 |
| P | GLY441 |
| site_id | KC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA P1587 |
| Chain | Residue |
| P | ARG270 |
| P | TYR273 |
| P | THR275 |
| P | HIS485 |
| P | ILE486 |
| site_id | KC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA P1588 |
| Chain | Residue |
| P | ARG106 |
| P | HOH2023 |
| site_id | KC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL P1589 |
| Chain | Residue |
| P | MSE38 |
| P | GLN64 |
| site_id | LC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL P1590 |
| Chain | Residue |
| P | TYR469 |
| P | PRO472 |
| P | GLY473 |
| P | SER523 |
| P | ILE526 |
| site_id | LC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL P1591 |
| Chain | Residue |
| N | LYS578 |
| P | CYS57 |
| P | PHE58 |
| site_id | LC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP A1581 |
| Chain | Residue |
| A | ARG165 |
| A | GLY168 |
| A | ASN259 |
| A | THR283 |
| A | GLY311 |
| A | ALA312 |
| A | GLY313 |
| A | GLU314 |
| A | ALA315 |
| A | VAL344 |
| A | ASP345 |
| A | SER346 |
| A | LYS362 |
| A | VAL392 |
| A | ALA393 |
| A | ALA394 |
| A | ILE395 |
| A | LEU419 |
| A | ASN421 |
| A | GLY446 |
| A | GLY465 |
| A | ASN466 |
| A | ASN467 |
| A | OXL1583 |
| A | HOH2034 |
| site_id | LC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAP B1581 |
| Chain | Residue |
| B | ARG165 |
| B | LEU167 |
| B | GLY168 |
| B | ASN259 |
| B | ASP279 |
| B | THR283 |
| B | GLN310 |
| B | GLY311 |
| B | ALA312 |
| B | GLY313 |
| B | GLU314 |
| B | ALA315 |
| B | VAL344 |
| B | ASP345 |
| B | SER346 |
| B | LYS362 |
| B | VAL392 |
| B | ALA393 |
| B | ALA394 |
| B | LEU419 |
| B | SER420 |
| B | ASN421 |
| B | GLY446 |
| B | GLY465 |
| B | ASN466 |
| B | ASN467 |
| B | OXL1582 |
| site_id | LC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAP C1581 |
| Chain | Residue |
| C | ARG165 |
| C | LEU167 |
| C | GLY168 |
| C | ASN259 |
| C | ASP279 |
| C | THR283 |
| C | GLN310 |
| C | GLY311 |
| C | ALA312 |
| C | GLY313 |
| C | GLU314 |
| C | ALA315 |
| C | VAL344 |
| C | ASP345 |
| C | SER346 |
| C | LYS362 |
| C | VAL392 |
| C | ALA393 |
| C | ALA394 |
| C | ILE395 |
| C | LEU419 |
| C | SER420 |
| C | ASN421 |
| C | GLY465 |
| C | ASN466 |
| C | ASN467 |
| C | OXL1582 |
| C | HOH2074 |
| C | HOH2075 |
| site_id | LC6 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP D1581 |
| Chain | Residue |
| D | ARG165 |
| D | GLY168 |
| D | ASN259 |
| D | THR283 |
| D | GLN310 |
| D | GLY311 |
| D | ALA312 |
| D | GLY313 |
| D | GLU314 |
| D | ALA315 |
| D | VAL344 |
| D | ASP345 |
| D | SER346 |
| D | LYS362 |
| D | VAL392 |
| D | ALA393 |
| D | ALA394 |
| D | ILE395 |
| D | LEU419 |
| D | SER420 |
| D | ASN421 |
| D | GLY465 |
| D | ASN466 |
| D | ASN467 |
| D | OXL1582 |
| D | HOH2028 |
| D | HOH2047 |
| D | HOH2048 |
| site_id | LC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAP E1581 |
| Chain | Residue |
| E | ARG165 |
| E | GLY168 |
| E | ASN259 |
| E | THR283 |
| E | GLN310 |
| E | GLY311 |
| E | ALA312 |
| E | GLY313 |
| E | GLU314 |
| E | ALA315 |
| E | VAL344 |
| E | ASP345 |
| E | SER346 |
| E | LYS362 |
| E | VAL392 |
| E | ALA393 |
| E | ALA394 |
| E | ILE395 |
| E | LEU419 |
| E | SER420 |
| E | ASN421 |
| E | GLY446 |
| E | GLY465 |
| E | ASN466 |
| E | ASN467 |
| E | OXL1582 |
| E | HOH2033 |
| E | HOH2055 |
| E | HOH2056 |
| site_id | LC8 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP F1581 |
| Chain | Residue |
| F | ARG165 |
| F | LEU167 |
| F | GLY168 |
| F | ASN259 |
| F | ASP279 |
| F | THR283 |
| F | GLN310 |
| F | GLY311 |
| F | ALA312 |
| F | GLY313 |
| F | GLU314 |
| F | ALA315 |
| F | VAL344 |
| F | ASP345 |
| F | SER346 |
| F | LYS362 |
| F | VAL392 |
| F | ALA393 |
| F | ALA394 |
| F | ILE395 |
| F | LEU419 |
| F | SER420 |
| F | ASN421 |
| F | GLY465 |
| F | ASN466 |
| F | ASN467 |
| F | OXL1582 |
| F | HOH2076 |
| site_id | LC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP G1581 |
| Chain | Residue |
| G | ARG165 |
| G | GLY168 |
| G | ASN259 |
| G | ASP279 |
| G | THR283 |
| G | GLY311 |
| G | ALA312 |
| G | GLY313 |
| G | GLU314 |
| G | ALA315 |
| G | VAL344 |
| G | ASP345 |
| G | SER346 |
| G | LYS362 |
| G | VAL392 |
| G | ALA393 |
| G | ALA394 |
| G | ILE395 |
| G | LEU419 |
| G | SER420 |
| G | ASN421 |
| G | GLY465 |
| G | ASN466 |
| G | ASN467 |
| G | OXL1582 |
| site_id | MC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP H1581 |
| Chain | Residue |
| H | ARG165 |
| H | LEU167 |
| H | GLY168 |
| H | ASN259 |
| H | ASP279 |
| H | THR283 |
| H | GLN310 |
| H | GLY311 |
| H | ALA312 |
| H | GLY313 |
| H | GLU314 |
| H | ALA315 |
| H | VAL344 |
| H | ASP345 |
| H | SER346 |
| H | LYS362 |
| H | VAL392 |
| H | ALA393 |
| H | ALA394 |
| H | ILE395 |
| H | LEU419 |
| H | ASN421 |
| H | GLY446 |
| H | GLY465 |
| H | ASN466 |
| H | ASN467 |
| H | OXL1582 |
| H | HOH2040 |
| site_id | MC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAP I1581 |
| Chain | Residue |
| I | ARG165 |
| I | LEU167 |
| I | GLY168 |
| I | ASN259 |
| I | ASP279 |
| I | THR283 |
| I | GLY311 |
| I | ALA312 |
| I | GLY313 |
| I | GLU314 |
| I | ALA315 |
| I | VAL344 |
| I | ASP345 |
| I | SER346 |
| I | LYS362 |
| I | VAL392 |
| I | ALA393 |
| I | ALA394 |
| I | ILE395 |
| I | LEU419 |
| I | SER420 |
| I | ASN421 |
| I | GLY446 |
| I | GLY465 |
| I | ASN466 |
| I | ASN467 |
| I | OXL1582 |
| I | HOH2077 |
| I | HOH2078 |
| I | HOH2079 |
| site_id | MC3 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP J1581 |
| Chain | Residue |
| J | ARG165 |
| J | LEU167 |
| J | GLY168 |
| J | ASN259 |
| J | ASP279 |
| J | THR283 |
| J | GLN310 |
| J | GLY311 |
| J | ALA312 |
| J | GLY313 |
| J | GLU314 |
| J | ALA315 |
| J | VAL344 |
| J | ASP345 |
| J | SER346 |
| J | LYS362 |
| J | VAL392 |
| J | ALA393 |
| J | ALA394 |
| J | ILE395 |
| J | LEU419 |
| J | SER420 |
| J | ASN421 |
| J | GLY446 |
| J | GLY465 |
| J | ASN466 |
| J | ASN467 |
| J | OXL1582 |
| site_id | MC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAP K1581 |
| Chain | Residue |
| K | ARG165 |
| K | GLY168 |
| K | ASN259 |
| K | ASP279 |
| K | THR283 |
| K | GLN310 |
| K | GLY311 |
| K | ALA312 |
| K | GLY313 |
| K | GLU314 |
| K | ALA315 |
| K | VAL344 |
| K | ASP345 |
| K | SER346 |
| K | LYS362 |
| K | VAL392 |
| K | ALA393 |
| K | ALA394 |
| K | ILE395 |
| K | LEU419 |
| K | SER420 |
| K | ASN421 |
| K | GLY446 |
| K | GLY465 |
| K | ASN466 |
| K | ASN467 |
| K | OXL1582 |
| site_id | MC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP L1581 |
| Chain | Residue |
| L | ARG165 |
| L | LEU167 |
| L | GLY168 |
| L | ASN259 |
| L | ASP279 |
| L | THR283 |
| L | GLN310 |
| L | GLY311 |
| L | ALA312 |
| L | GLY313 |
| L | GLU314 |
| L | ALA315 |
| L | VAL344 |
| L | ASP345 |
| L | SER346 |
| L | LYS362 |
| L | VAL392 |
| L | ALA393 |
| L | ALA394 |
| L | ILE395 |
| L | LEU419 |
| L | ASN421 |
| L | GLY446 |
| L | GLY465 |
| L | ASN466 |
| L | ASN467 |
| L | OXL1582 |
| L | HOH2073 |
| site_id | MC6 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAP M1581 |
| Chain | Residue |
| M | ARG165 |
| M | LEU167 |
| M | GLY168 |
| M | ASN259 |
| M | ASP279 |
| M | THR283 |
| M | GLN310 |
| M | GLY311 |
| M | ALA312 |
| M | GLY313 |
| M | GLU314 |
| M | ALA315 |
| M | VAL344 |
| M | ASP345 |
| M | SER346 |
| M | LYS362 |
| M | VAL392 |
| M | ALA393 |
| M | ALA394 |
| M | ILE395 |
| M | LEU419 |
| M | ASN421 |
| M | GLY446 |
| M | GLY465 |
| M | ASN466 |
| M | ASN467 |
| M | OXL1582 |
| site_id | MC7 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP N1581 |
| Chain | Residue |
| N | ARG165 |
| N | LEU167 |
| N | GLY168 |
| N | ASN259 |
| N | THR283 |
| N | GLN310 |
| N | GLY311 |
| N | ALA312 |
| N | GLY313 |
| N | GLU314 |
| N | ALA315 |
| N | VAL344 |
| N | ASP345 |
| N | SER346 |
| N | LYS362 |
| N | VAL392 |
| N | ALA393 |
| N | ALA394 |
| N | LEU419 |
| N | SER420 |
| N | ASN421 |
| N | GLY446 |
| N | GLY465 |
| N | ASN466 |
| N | ASN467 |
| N | OXL1582 |
| N | HOH2069 |
| N | HOH2070 |
| site_id | MC8 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAP O1581 |
| Chain | Residue |
| O | ARG165 |
| O | LEU167 |
| O | GLY168 |
| O | ASN259 |
| O | ASP279 |
| O | THR283 |
| O | GLN310 |
| O | GLY311 |
| O | ALA312 |
| O | GLY313 |
| O | GLU314 |
| O | ALA315 |
| O | VAL344 |
| O | ASP345 |
| O | SER346 |
| O | LYS362 |
| O | VAL392 |
| O | ALA393 |
| O | ALA394 |
| O | ILE395 |
| O | LEU419 |
| O | SER420 |
| O | ASN421 |
| O | GLY446 |
| O | GLY465 |
| O | ASN466 |
| O | ASN467 |
| O | OXL1582 |
| O | HOH2049 |
| O | HOH2077 |
| site_id | MC9 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAP P1581 |
| Chain | Residue |
| P | ARG165 |
| P | LEU167 |
| P | GLY168 |
| P | ASN259 |
| P | ASP279 |
| P | THR283 |
| P | GLN310 |
| P | GLY311 |
| P | ALA312 |
| P | GLY313 |
| P | GLU314 |
| P | ALA315 |
| P | VAL344 |
| P | ASP345 |
| P | SER346 |
| P | LYS362 |
| P | VAL392 |
| P | ALA393 |
| P | ALA394 |
| P | LEU419 |
| P | ASN421 |
| P | GLY446 |
| P | GLY465 |
| P | ASN466 |
| P | ASN467 |
| P | OXL1582 |
| P | HOH2079 |
Functional Information from PROSITE/UniProt
| site_id | PS00331 |
| Number of Residues | 17 |
| Details | MALIC_ENZYMES Malic enzymes signature. FnDDiqGTAsVaVAGLL |
| Chain | Residue | Details |
| A | PHE276-LEU292 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11790843","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"11790843","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 192 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11790843","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Site: {"description":"Important for activity"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Site: {"description":"Confers specificity for NADP"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| A | ASP278 | |
| A | LYS183 | |
| A | TYR112 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| B | ASP278 | |
| B | LYS183 | |
| B | TYR112 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| C | ASP278 | |
| C | LYS183 | |
| C | TYR112 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| D | ASP278 | |
| D | LYS183 | |
| D | TYR112 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| E | ASP278 | |
| E | LYS183 | |
| E | TYR112 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| F | ASP278 | |
| F | LYS183 | |
| F | TYR112 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| G | ASP278 | |
| G | LYS183 | |
| G | TYR112 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| H | ASP278 | |
| H | LYS183 | |
| H | TYR112 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| I | ASP278 | |
| I | LYS183 | |
| I | TYR112 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| J | ASP278 | |
| J | LYS183 | |
| J | TYR112 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| K | ASP278 | |
| K | LYS183 | |
| K | TYR112 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| L | ASP278 | |
| L | LYS183 | |
| L | TYR112 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| M | ASP278 | |
| M | LYS183 | |
| M | TYR112 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| N | ASP278 | |
| N | LYS183 | |
| N | TYR112 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| O | ASP278 | |
| O | LYS183 | |
| O | TYR112 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| P | ASP278 | |
| P | LYS183 | |
| P | TYR112 |
