1GCW

CO form hemoglobin from mustelus griseus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0043177	molecular_function	organic acid binding
A	0046872	molecular_function	metal ion binding
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0031720	molecular_function	haptoglobin binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0043177	molecular_function	organic acid binding
B	0046872	molecular_function	metal ion binding
B	0072562	cellular_component	blood microparticle
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005344	molecular_function	oxygen carrier activity
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031720	molecular_function	haptoglobin binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0043177	molecular_function	organic acid binding
C	0046872	molecular_function	metal ion binding
C	0072562	cellular_component	blood microparticle
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005344	molecular_function	oxygen carrier activity
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0031720	molecular_function	haptoglobin binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0043177	molecular_function	organic acid binding
D	0046872	molecular_function	metal ion binding
D	0072562	cellular_component	blood microparticle
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM A 141

Chain	Residue
A	TYR42
A	LEU101
A	CYS132
A	LEU135
A	CMO142
B	LYS13
A	PHE43
A	HIS58
A	LYS61
A	ALA65
A	HIS87
A	LEU91
A	ASN97
A	PHE98

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CMO A 142

Chain	Residue
A	HIS58
A	VAL62
A	HEM141

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM B 136

Chain	Residue
B	MET31
B	TYR41
B	PHE42
B	HIS53
B	LEU78
B	HIS82
B	LEU86
B	VAL88
B	SER92
B	PHE93
B	ILE131
B	CMO137

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CMO B 137

Chain	Residue
B	HIS53
B	VAL57
B	HEM136

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE HEM C 141

Chain	Residue
C	TYR42
C	PHE43
C	HIS58
C	LEU83
C	HIS87
C	LEU91
C	ASN97
C	PHE98
C	LEU101
C	LEU135
C	CMO142
C	HOH1055

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CMO C 142

Chain	Residue
C	HIS58
C	VAL62
C	HEM141

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM D 136

Chain	Residue
D	TYR41
D	PHE42
D	HIS53
D	ILE56
D	LYS81
D	HIS82
D	SER92
D	PHE93
D	LEU96
D	ILE131
D	CMO137

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CMO D 137

Chain	Residue
D	HIS53
D	VAL57
D	HEM136

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	278
Details	Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"description":"distal binding residue","evidences":[{"source":"PubMed","id":"11243818","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"11243818","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GCV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GCW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---