Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1G29

MALK

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000166	molecular_function	nucleotide binding
1	0005524	molecular_function	ATP binding
1	0005886	cellular_component	plasma membrane
1	0008643	biological_process	carbohydrate transport
1	0015423	molecular_function	ABC-type maltose transporter activity
1	0016887	molecular_function	ATP hydrolysis activity
1	0022857	molecular_function	transmembrane transporter activity
1	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
1	0046872	molecular_function	metal ion binding
1	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
1	0055085	biological_process	transmembrane transport
1	0140359	molecular_function	ABC-type transporter activity
1	1902495	cellular_component	transmembrane transporter complex
1	1904981	biological_process	maltose transmembrane transport
2	0000166	molecular_function	nucleotide binding
2	0005524	molecular_function	ATP binding
2	0005886	cellular_component	plasma membrane
2	0008643	biological_process	carbohydrate transport
2	0015423	molecular_function	ABC-type maltose transporter activity
2	0016887	molecular_function	ATP hydrolysis activity
2	0022857	molecular_function	transmembrane transporter activity
2	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
2	0046872	molecular_function	metal ion binding
2	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
2	0055085	biological_process	transmembrane transport
2	0140359	molecular_function	ABC-type transporter activity
2	1902495	cellular_component	transmembrane transporter complex
2	1904981	biological_process	maltose transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NH4 1 373

Chain	Residue
1	GLY29
1	LYS183
1	GLN186
1	ASP208
1	HOH959

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NH4 2 373

Chain	Residue
2	GLY29
2	LYS183
2	GLN186
2	ASP208

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NH4 2 374

Chain	Residue
1	ALA180
1	LYS184
2	GLU347
2	HOH631
2	HOH646

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 2 375

Chain	Residue
2	ASP293
2	TYR295
2	ASP356

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL 1 374

Chain	Residue
1	VAL227
1	VAL236
1	ALA237
1	ILE240
1	ARG290

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL 2 376

Chain	Residue
2	VAL227
2	VAL236
2	ALA237
2	ILE240
2	ARG290

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA 2 377

Chain	Residue
1	ALA180
1	THR205
1	HOH834
1	HOH858
2	ILE316
2	GLU347

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL 2 378

Chain	Residue
1	GLU318
2	ARG179
2	HOH516

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL 1 375

Chain	Residue
1	THR43
1	ARG47
1	HOH878
2	SER89
2	LEU92

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA 1 376

Chain	Residue
1	GLU292
1	MG392
2	GLY321
2	SER322
2	SER341

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA 1 377

Chain	Residue
1	ILE316
1	VAL317
1	GLU347
2	ALA180
2	THR205
2	HOH516
2	HOH520

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 2 379

Chain	Residue
2	GLU292
2	ASP293
2	LYS359
2	NA388

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 1 378

Chain	Residue
1	GLU292
1	ASP293
1	LYS359
1	NA385

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 2 380

Chain	Residue
2	SER38
2	GLY39
2	HOH545

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 379

Chain	Residue
1	LYS11
1	GLU53
1	HOH841

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL 2 381

Chain	Residue
2	THR17
2	ARG20
2	ARG215

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 1 380

Chain	Residue
1	GLU30
1	HOH970

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 382

Chain	Residue
2	ASP229
2	HOH645

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA 2 383

Chain	Residue
1	ASN319
1	ARG324
1	HOH891
2	MET204
2	PRO224
2	ASP225

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL 1 381

Chain	Residue
1	ARG121
1	HOH874

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA 2 384

Chain	Residue
2	GLU315

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 385

Chain	Residue
1	LYS183
1	THR205
1	HOH858
2	GLU347
2	HOH525

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA 1 382

Chain	Residue
1	GLU347
1	HOH863
2	LYS183
2	THR205
2	HOH520

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 383

Chain	Residue
1	ASP296
1	MET298
1	HOH1017

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 386

Chain	Residue
2	PHE13
2	GLU53
1	LYS79
1	ASP80
2	LYS11

site_id	CC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 2 387

Chain	Residue
1	ARG324
1	HOH925
1	HOH978
2	ASP225
2	NA394

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 1 384

Chain	Residue
1	GLN59
1	ASP69
1	GLU71
1	LYS72

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA 1 385

Chain	Residue
1	ASP229
1	LYS359
1	MG378
1	HOH975

site_id	DC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 1 386

Chain	Residue
1	GLU181
1	HOH850

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 1 387

Chain	Residue
1	ASP225
1	HOH918

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 388

Chain	Residue
1	ASP225
2	ARG324
2	SER341

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA 2 388

Chain	Residue
2	ASP229
2	MG379
2	NA424
2	HOH639

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 389

Chain	Residue
1	ARG209
1	GLU226
1	HOH922

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 389

Chain	Residue
2	THR43
2	ASP164

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 390

Chain	Residue
2	GLU181
2	LYS184

site_id	DC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 391

Chain	Residue
1	HOH928
2	ASP80

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 392

Chain	Residue
2	GLU30
2	ARG209

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 1 390

Chain	Residue
1	ASP229
1	HOH1016

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 2 393

Chain	Residue
2	SER223
2	GLU226

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA 2 394

Chain	Residue
1	ARG324
1	SER341
2	ASP225
2	MG387
2	HOH648

site_id	EC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL 2 395

Chain	Residue
2	ARG20
2	ARG215

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL 1 391

Chain	Residue
1	ARG344

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 1 392

Chain	Residue
1	ASP229
1	NA376

site_id	EC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 1 393

Chain	Residue
1	SER341
1	GLU342
1	HOH847
2	HOH544
2	HOH651

site_id	EC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL 2 396

Chain	Residue
1	ALA297
1	ASP352
2	ARG303

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 1 394

Chain	Residue
1	GLU131
2	ARG147

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 397

Chain	Residue
2	ASP356
2	LYS359

site_id	FC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 414

Chain	Residue
1	GLU347
2	ALA180
2	LYS184

site_id	FC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 1 422

Chain	Residue
1	ASP82
1	ARG156
1	LYS157

site_id	FC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA 2 424

Chain	Residue
2	ASP229
2	NA388
2	HOH544

site_id	FC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL 2 430

Chain	Residue
2	ARG121
2	HOH565

site_id	FC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA 2 439

Chain	Residue
2	GLU54
2	HOH684

site_id	FC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE POP 2 500

Chain	Residue
1	TYR93
2	PRO37
2	SER38
2	GLY39
2	CYS40
2	GLY41
2	LYS42
2	THR43
2	THR44
2	HOH680

site_id	FC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE POP 1 501

Chain	Residue
1	PRO37
1	SER38
1	GLY39
1	CYS40
1	GLY41
1	LYS42
1	THR43
1	THR44
1	HOH836
2	TYR93
2	HIS95

site_id	GC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DIO 1 830

Chain	Residue
1	TRP10
1	ARG57
2	TRP10
2	ARG57

site_id	GC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DIO 1 831

Chain	Residue
1	GLY14
1	DIO832
2	SER56

site_id	GC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DIO 1 832

Chain	Residue
1	SER56
1	DIO831
2	GLY14
2	HOH510

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRVALGRAI

Chain	Residue	Details
1	LEU140-ILE154

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	472
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)