1G0H
CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE-FRUCTOSE 1,6 BISPHOSPHATASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006020 | biological_process | inositol metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
| B | 0006020 | biological_process | inositol metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 290 |
| Chain | Residue |
| A | GLU65 |
| A | ASP81 |
| A | ASP84 |
| A | ASP201 |
| A | IPD292 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 291 |
| Chain | Residue |
| A | HOH620 |
| A | HOH621 |
| A | GLU65 |
| A | ASP81 |
| A | ILE83 |
| A | IPD292 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 590 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ILE383 |
| B | IPD592 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 591 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ASP384 |
| B | ASP501 |
| B | IPD592 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IPD A 292 |
| Chain | Residue |
| A | GLU65 |
| A | ASP81 |
| A | ILE83 |
| A | ASP84 |
| A | GLY85 |
| A | SER86 |
| A | ALA174 |
| A | PHE175 |
| A | ARG194 |
| A | ASP201 |
| A | CA290 |
| A | CA291 |
| A | HOH620 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE IPD B 592 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ILE383 |
| B | ASP384 |
| B | GLY385 |
| B | SER386 |
| B | PHE475 |
| B | ARG494 |
| B | LYS496 |
| B | ARG498 |
| B | ASP501 |
| B | CA590 |
| B | CA591 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11062561","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"11170378","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11170378","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP44 | |
| A | GLU66 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| B | ASP338 | |
| B | GLU366 | |
| B | ASP344 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| A | SER86 | |
| A | GLU65 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| B | SER386 | |
| B | GLU365 |
