1FZ5

METHANE MONOOXYGENASE HYDROXYLASE, FORM II CRYSTALLIZED ANAEROBICALLY FROM REDUCED ENZYME

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0006725	biological_process	obsolete cellular aromatic compound metabolic process
A	0006730	biological_process	one-carbon metabolic process
A	0015049	molecular_function	methane monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0106317	molecular_function	methane monooxygenase NADH activity
A	0106318	molecular_function	methane monooxygenase NADPH activity
B	0004497	molecular_function	monooxygenase activity
B	0005515	molecular_function	protein binding
B	0006725	biological_process	obsolete cellular aromatic compound metabolic process
B	0006730	biological_process	one-carbon metabolic process
B	0015049	molecular_function	methane monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0106317	molecular_function	methane monooxygenase NADH activity
B	0106318	molecular_function	methane monooxygenase NADPH activity
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0006725	biological_process	obsolete cellular aromatic compound metabolic process
C	0006730	biological_process	one-carbon metabolic process
C	0015049	molecular_function	methane monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
C	0106317	molecular_function	methane monooxygenase NADH activity
C	0106318	molecular_function	methane monooxygenase NADPH activity
D	0004497	molecular_function	monooxygenase activity
D	0005515	molecular_function	protein binding
D	0006725	biological_process	obsolete cellular aromatic compound metabolic process
D	0006730	biological_process	one-carbon metabolic process
D	0015049	molecular_function	methane monooxygenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
D	0106317	molecular_function	methane monooxygenase NADH activity
D	0106318	molecular_function	methane monooxygenase NADPH activity
E	0004497	molecular_function	monooxygenase activity
E	0006730	biological_process	one-carbon metabolic process
E	0015049	molecular_function	methane monooxygenase activity
E	0015947	biological_process	methane metabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0106317	molecular_function	methane monooxygenase NADH activity
E	0106318	molecular_function	methane monooxygenase NADPH activity
F	0004497	molecular_function	monooxygenase activity
F	0006730	biological_process	one-carbon metabolic process
F	0015049	molecular_function	methane monooxygenase activity
F	0015947	biological_process	methane metabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0106317	molecular_function	methane monooxygenase NADH activity
F	0106318	molecular_function	methane monooxygenase NADPH activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE2 A 5001

Chain	Residue
A	GLU114
A	GLU144
A	HIS147
A	HIS246

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 B 5003

Chain	Residue
B	GLU114
B	GLU144
B	HIS147
B	GLU243
B	HIS246

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 5005

Chain	Residue
A	ASN527
A	HOH5098
A	HOH5099
A	HOH5127
B	SER428

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 5006

Chain	Residue
C	ASP348
C	GLU350
C	HOH5114
C	HOH5115
C	HOH5116

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255

Chain	Residue	Details
A	CYS151
B	CYS151

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	GLU114
B	GLU209
B	GLU243
B	HIS246
A	GLU144
A	HIS147
A	GLU209
A	GLU243
A	HIS246
B	GLU114
B	GLU144
B	HIS147

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