1FOS

TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0003677	molecular_function	DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00036
Number of Residues	16
Details	BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. RkrmRNRiAASKsRKR

Chain	Residue	Details
F	ARG266-ARG281
E	ARG143-ARG157

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Necessary for synergistic transcriptional activity with SMAD3

Chain	Residue	Details
F	ARG281
H	ARG281

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:11689449

Chain	Residue	Details
F	LYS280
H	LYS280

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by PAK2 => ECO:0000269|PubMed:21177766

Chain	Residue	Details
F	THR295
H	THR295

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