1FN9

CRYSTAL STRUCTURE OF THE REOVIRUS OUTER CAPSID PROTEIN SIGMA 3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005198	molecular_function	structural molecule activity
A	0008270	molecular_function	zinc ion binding
A	0019028	cellular_component	viral capsid
A	0019058	biological_process	viral life cycle
A	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
A	0030430	cellular_component	host cell cytoplasm
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
A	0039624	cellular_component	viral outer capsid
A	0042025	cellular_component	host cell nucleus
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0003723	molecular_function	RNA binding
B	0005198	molecular_function	structural molecule activity
B	0008270	molecular_function	zinc ion binding
B	0019028	cellular_component	viral capsid
B	0019058	biological_process	viral life cycle
B	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
B	0030430	cellular_component	host cell cytoplasm
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
B	0039624	cellular_component	viral outer capsid
B	0042025	cellular_component	host cell nucleus
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1001

Chain	Residue
A	CYS51
A	CYS54
A	HIS71
A	CYS73

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1002

Chain	Residue
B	CYS51
B	CYS54
B	HIS71
B	CYS73

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cmh..ClgvVgslqrklkHlph..H

Chain	Residue	Details
A	CYS51-HIS71

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Zinc finger: {"description":"CCHC-type","evidences":[{"source":"PubMed","id":"11230122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---