1FLC
X-RAY STRUCTURE OF THE HAEMAGGLUTININ-ESTERASE-FUSION GLYCOPROTEIN OF INFLUENZA C VIRUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0046789 | molecular_function | host cell surface receptor binding |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0046789 | molecular_function | host cell surface receptor binding |
| C | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| C | 0019031 | cellular_component | viral envelope |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0046789 | molecular_function | host cell surface receptor binding |
| D | 0019031 | cellular_component | viral envelope |
| D | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| D | 0046789 | molecular_function | host cell surface receptor binding |
| E | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| E | 0019031 | cellular_component | viral envelope |
| E | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| E | 0046789 | molecular_function | host cell surface receptor binding |
| F | 0019031 | cellular_component | viral envelope |
| F | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| F | 0046789 | molecular_function | host cell surface receptor binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 75 |
| Details | Region: {"description":"Fusion domain-1","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 351 |
| Details | Region: {"description":"Esterase domain-1","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 330 |
| Details | Region: {"description":"Esterase domain-1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 477 |
| Details | Region: {"description":"N-acetyl-9-O-acetylneuraminic acid binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 456 |
| Details | Region: {"description":"N-acetyl-9-O-acetylneuraminic acid binding","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 162 |
| Details | Region: {"description":"Esterase domain-2","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 162 |
| Details | Region: {"description":"Esterase domain-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 21 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04072","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
