1FID
STRUCTURE OF HUMAN GAMMA FIBRINOGEN 30 KD CARBOXYL TERMINAL FRAGMENT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007596 | biological_process | blood coagulation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 500 |
| Chain | Residue |
| A | PHE322 |
| A | GLY324 |
| A | HOH501 |
| A | HOH502 |
| A | ASP318 |
| A | ASP320 |
| site_id | CAB |
| Number of Residues | 7 |
| Details | CALCIUM-BINDING SITE |
| Chain | Residue |
| A | CA500 |
| A | ASP318 |
| A | ASP320 |
| A | PHE322 |
| A | GLY324 |
| A | HOH502 |
| A | HOH503 |
Functional Information from PROSITE/UniProt
| site_id | PS00514 |
| Number of Residues | 13 |
| Details | FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWMnkChaGhlNG |
| Chain | Residue | Details |
| A | TRP334-GLY346 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 246 |
| Details | Domain: {"description":"Fibrinogen C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00739","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Region: {"description":"Gamma-chain polymerization, binding amino end of another fibrin alpha chain"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10074346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19296670","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9016719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9207064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9333233","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9628725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FID","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; in variant Asahi"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-432)"} |
| Chain | Residue | Details |
