1FHW
Structure of the pleckstrin homology domain from GRP1 in complex with inositol(1,3,4,5,6)pentakisphosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2001 |
| Chain | Residue |
| A | ASN312 |
| A | ASN331 |
| B | HOH31 |
| B | LYS340 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE I5P A 1001 |
| Chain | Residue |
| A | HOH156 |
| A | LYS273 |
| A | GLY276 |
| A | ARG277 |
| A | LYS282 |
| A | ARG284 |
| A | TYR295 |
| A | ARG305 |
| A | LYS343 |
| A | HIS355 |
| A | HOH12 |
| A | HOH46 |
| A | HOH48 |
| A | HOH50 |
| A | HOH121 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE I5P B 1002 |
| Chain | Residue |
| B | HOH22 |
| B | HOH139 |
| B | HOH140 |
| B | HOH141 |
| B | LYS273 |
| B | GLY275 |
| B | GLY276 |
| B | ARG277 |
| B | VAL278 |
| B | ARG284 |
| B | TYR295 |
| B | ARG305 |
| B | LYS343 |
| B | HIS355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS273 | |
| B | LYS273 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10983984, ECO:0000269|PubMed:15359279 |
| Chain | Residue | Details |
| A | ARG284 | |
| A | TYR295 | |
| A | ARG305 | |
| A | ASN354 | |
| B | ARG284 | |
| B | TYR295 | |
| B | ARG305 | |
| B | ASN354 |
