1F9V
CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 997 |
| Chain | Residue |
| A | THR481 |
| A | ADP999 |
| A | HOH1097 |
| A | HOH1098 |
| A | HOH1099 |
| A | HOH1104 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ADP A 999 |
| Chain | Residue |
| A | GLN475 |
| A | THR476 |
| A | GLY477 |
| A | SER478 |
| A | GLY479 |
| A | LYS480 |
| A | THR481 |
| A | PHE482 |
| A | MG997 |
| A | HOH1011 |
| A | HOH1049 |
| A | HOH1063 |
| A | HOH1097 |
| A | HOH1099 |
| A | HOH1104 |
| A | HOH1143 |
| A | HOH1177 |
| A | HOH1202 |
| A | ARG392 |
| A | ARG394 |
| A | PRO395 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP A 998 |
| Chain | Residue |
| A | ASN386 |
| A | ARG388 |
| A | GLU454 |
| A | GLN457 |
| A | LEU458 |
| A | THR694 |
| A | LEU695 |
| A | HOH1029 |
| A | HOH1135 |
| A | HOH1269 |
| A | HOH1331 |
| A | HOH1354 |
| A | HOH1357 |
Functional Information from PROSITE/UniProt
| site_id | PS00411 |
| Number of Residues | 12 |
| Details | KINESIN_MOTOR_1 Kinesin motor domain signature. GTLnLVDLAGSE |
| Chain | Residue | Details |
| A | GLY620-GLU631 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22734002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9485302","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F9W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ETP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11387196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F9W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22734002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ETP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1goj |
| Chain | Residue | Details |
| A | GLY629 |
