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1F9P

CRYSTAL STRUCTURE OF CONNECTIVE TISSUE ACTIVATING PEPTIDE-III(CTAP-III) COMPLEXED WITH POLYVINYLSULFONIC ACID

Functional Information from GO Data
ChainGOidnamespacecontents
A0005125molecular_functioncytokine activity
A0005355molecular_functionglucose transmembrane transporter activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006935biological_processchemotaxis
A0006952biological_processdefense response
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0008009molecular_functionchemokine activity
A0008083molecular_functiongrowth factor activity
A0030593biological_processneutrophil chemotaxis
A0031093cellular_componentplatelet alpha granule lumen
A0042742biological_processdefense response to bacterium
A0045236molecular_functionCXCR chemokine receptor binding
A0051781biological_processpositive regulation of cell division
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070098biological_processchemokine-mediated signaling pathway
A0071222biological_processcellular response to lipopolysaccharide
A1904659biological_processglucose transmembrane transport
A1904724cellular_componenttertiary granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ESA A 101
ChainResidue
AHIS35
APRO36
AARG74
AESA102
AESA103
AESA103

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ESA A 102
ChainResidue
AESA103
AESA103
AHIS35
ALYS37
AESA101

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE ESA A 103
ChainResidue
AHIS35
APRO36
ALYS37
ALYS81
ALYS81
AESA101
AESA101
AESA102
AESA102
AHOH324

Functional Information from PROSITE/UniProt
site_idPS00471
Number of Residues45
DetailsSMALL_CYTOKINES_CXC Small cytokines (intercrine/chemokine) C-x-C subfamily signature. CmCIkttsg.IhpKnIqsLevigkGthCnqvEVIatlkdgrki.CLD
ChainResidueDetails
ACYS25-ASP69

222415

PDB entries from 2024-07-10

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