Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1F7T

HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
A	0016740	molecular_function	transferase activity
A	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
B	0016740	molecular_function	transferase activity
B	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
C	0016740	molecular_function	transferase activity
C	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
D	0016740	molecular_function	transferase activity
D	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006633	biological_process	fatty acid biosynthetic process
E	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
E	0016740	molecular_function	transferase activity
E	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006629	biological_process	lipid metabolic process
F	0006631	biological_process	fatty acid metabolic process
F	0006633	biological_process	fatty acid biosynthetic process
F	0008897	molecular_function	holo-[acyl-carrier-protein] synthase activity
F	0016740	molecular_function	transferase activity
F	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 472

Chain	Residue
A	HIS105
A	HOH536
B	ILE9
B	CL490
B	HOH528

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 473

Chain	Residue
C	HOH543
B	VAL101
B	CL484
B	HOH529
C	CL491

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 474

Chain	Residue
A	ILE9
A	CL494
A	HOH526
C	HIS105
C	HOH564

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA D 475

Chain	Residue
D	HIS105
D	HOH547
E	ILE9
E	CL482
E	HOH528

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA E 476

Chain	Residue
E	HIS105
E	HOH543
F	ILE9
F	CL485
F	HOH539

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA D 478

Chain	Residue
D	ILE9
D	CL492
D	HOH544
F	HIS105
F	HOH546

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 479

Chain	Residue
B	HIS105
B	HOH544
C	ILE9
C	CL483
C	HOH551

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 480

Chain	Residue
A	GLU27
A	GLN75
A	HOH520
A	HOH557
A	HOH565

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 481

Chain	Residue
A	ARG80
A	LYS81

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL E 482

Chain	Residue
D	NA475
E	GLU11
E	ARG14
E	HOH515

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 483

Chain	Residue
B	NA479
C	GLU11
C	ARG14

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 484

Chain	Residue
B	VAL101
B	NA473
B	HOH519
C	CL491
D	ARG24

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL F 485

Chain	Residue
E	NA476
F	THR10
F	GLU11
F	ARG14
F	HOH534

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL F 486

Chain	Residue
F	LYS86
F	PRO87
F	SER102
F	ILE103

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 487

Chain	Residue
A	LYS86
A	PRO87
A	SER102
A	ILE103
A	HOH576

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL C 489

Chain	Residue
C	LYS86
C	PRO87
C	SER102
C	ILE103
C	DTT502
C	HOH519

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 490

Chain	Residue
A	NA472
B	THR10
B	GLU11
B	ARG14

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL C 491

Chain	Residue
B	NA473
B	CL484
B	HOH510
C	GLY4
C	ILE5
D	LYS23

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 492

Chain	Residue
D	GLU11
D	ARG14
D	NA478

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 493

Chain	Residue
A	THR106
A	LYS107
A	GLU108
B	TYR109
B	HOH540

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 494

Chain	Residue
A	GLU11
A	ARG14
A	HOH525
C	NA474

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL D 495

Chain	Residue
E	TYR109
E	HOH491
D	THR106
D	LYS107
D	GLU108

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL F 496

Chain	Residue
D	GLY4
D	ILE5
D	GOL506
F	LYS86
F	HIS100
F	VAL101
F	HOH508

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 497

Chain	Residue
D	LYS86
D	SER102
D	ILE103
D	DTT505

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 498

Chain	Residue
C	ARG32
F	HOH530

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL C 499

Chain	Residue
A	TYR109
C	THR106
C	LYS107
C	GLU108

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL D 500

Chain	Residue
D	LYS86
D	HIS100
D	VAL101
D	HOH517
E	GLY4
E	ILE5

site_id	DC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DTT A 501

Chain	Residue
A	ASN84
A	GLY85
A	LYS86
A	HOH576
B	THR66

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DTT C 502

Chain	Residue
A	GLY65
A	THR66
C	ASN84
C	LYS86
C	CL489
C	HOH519

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DTT D 503

Chain	Residue
D	ASP76
D	GLU78
D	CYS91
D	HOH560

site_id	DC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DTT F 504

Chain	Residue
D	GLY65
D	THR66
F	ASN84
F	LYS86
F	HOH509

site_id	DC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DTT D 505

Chain	Residue
D	ASN84
D	GLY85
D	LYS86
D	CL497
E	GLY65
E	THR66

site_id	DC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL D 506

Chain	Residue
C	ARG24
D	TYR3
D	LYS62
D	ALA63
D	PHE64
D	GLY65
F	LYS86
F	CL496

site_id	DC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 507

Chain	Residue
B	GLN75
B	ASP76
B	GLU78
B	ILE90
B	CYS91
B	THR92
B	HOH556
B	HOH570

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
A	LYS62
A	HIS105

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
B	LYS62
B	HIS105

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
C	LYS62
C	HIS105

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
D	LYS62
D	HIS105

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
E	LYS62
E	HIS105

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1f7l

Chain	Residue	Details
F	LYS62
F	HIS105

site_id	MCSA1
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
A	LYS62	electrostatic stabiliser
A	HIS105	electrostatic stabiliser

site_id	MCSA2
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
B	LYS62	electrostatic stabiliser
B	HIS105	electrostatic stabiliser

site_id	MCSA3
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
C	LYS62	electrostatic stabiliser
C	HIS105	electrostatic stabiliser

site_id	MCSA4
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
D	LYS62	electrostatic stabiliser
D	HIS105	electrostatic stabiliser

site_id	MCSA5
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
E	LYS62	electrostatic stabiliser
E	HIS105	electrostatic stabiliser

site_id	MCSA6
Number of Residues	2
Details	M-CSA 152

Chain	Residue	Details
F	LYS62	electrostatic stabiliser
F	HIS105	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)