Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1F52

CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006541	biological_process	glutamine metabolic process
A	0006542	biological_process	glutamine biosynthetic process
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019740	biological_process	nitrogen utilization
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
A	0051260	biological_process	protein homooligomerization
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006541	biological_process	glutamine metabolic process
B	0006542	biological_process	glutamine biosynthetic process
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019740	biological_process	nitrogen utilization
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
B	0051260	biological_process	protein homooligomerization
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006541	biological_process	glutamine metabolic process
C	0006542	biological_process	glutamine biosynthetic process
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0019740	biological_process	nitrogen utilization
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding
C	0051260	biological_process	protein homooligomerization
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006541	biological_process	glutamine metabolic process
D	0006542	biological_process	glutamine biosynthetic process
D	0016020	cellular_component	membrane
D	0016874	molecular_function	ligase activity
D	0019740	biological_process	nitrogen utilization
D	0030145	molecular_function	manganese ion binding
D	0046872	molecular_function	metal ion binding
D	0051260	biological_process	protein homooligomerization
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0004356	molecular_function	glutamine synthetase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006541	biological_process	glutamine metabolic process
E	0006542	biological_process	glutamine biosynthetic process
E	0016020	cellular_component	membrane
E	0016874	molecular_function	ligase activity
E	0019740	biological_process	nitrogen utilization
E	0030145	molecular_function	manganese ion binding
E	0046872	molecular_function	metal ion binding
E	0051260	biological_process	protein homooligomerization
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0004356	molecular_function	glutamine synthetase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006541	biological_process	glutamine metabolic process
F	0006542	biological_process	glutamine biosynthetic process
F	0016020	cellular_component	membrane
F	0016874	molecular_function	ligase activity
F	0019740	biological_process	nitrogen utilization
F	0030145	molecular_function	manganese ion binding
F	0046872	molecular_function	metal ion binding
F	0051260	biological_process	protein homooligomerization
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0004356	molecular_function	glutamine synthetase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006541	biological_process	glutamine metabolic process
G	0006542	biological_process	glutamine biosynthetic process
G	0016020	cellular_component	membrane
G	0016874	molecular_function	ligase activity
G	0019740	biological_process	nitrogen utilization
G	0030145	molecular_function	manganese ion binding
G	0046872	molecular_function	metal ion binding
G	0051260	biological_process	protein homooligomerization
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0004356	molecular_function	glutamine synthetase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006541	biological_process	glutamine metabolic process
H	0006542	biological_process	glutamine biosynthetic process
H	0016020	cellular_component	membrane
H	0016874	molecular_function	ligase activity
H	0019740	biological_process	nitrogen utilization
H	0030145	molecular_function	manganese ion binding
H	0046872	molecular_function	metal ion binding
H	0051260	biological_process	protein homooligomerization
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0004356	molecular_function	glutamine synthetase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006541	biological_process	glutamine metabolic process
I	0006542	biological_process	glutamine biosynthetic process
I	0016020	cellular_component	membrane
I	0016874	molecular_function	ligase activity
I	0019740	biological_process	nitrogen utilization
I	0030145	molecular_function	manganese ion binding
I	0046872	molecular_function	metal ion binding
I	0051260	biological_process	protein homooligomerization
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0004356	molecular_function	glutamine synthetase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006541	biological_process	glutamine metabolic process
J	0006542	biological_process	glutamine biosynthetic process
J	0016020	cellular_component	membrane
J	0016874	molecular_function	ligase activity
J	0019740	biological_process	nitrogen utilization
J	0030145	molecular_function	manganese ion binding
J	0046872	molecular_function	metal ion binding
J	0051260	biological_process	protein homooligomerization
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0004356	molecular_function	glutamine synthetase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0006541	biological_process	glutamine metabolic process
K	0006542	biological_process	glutamine biosynthetic process
K	0016020	cellular_component	membrane
K	0016874	molecular_function	ligase activity
K	0019740	biological_process	nitrogen utilization
K	0030145	molecular_function	manganese ion binding
K	0046872	molecular_function	metal ion binding
K	0051260	biological_process	protein homooligomerization
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006541	biological_process	glutamine metabolic process
L	0006542	biological_process	glutamine biosynthetic process
L	0016020	cellular_component	membrane
L	0016874	molecular_function	ligase activity
L	0019740	biological_process	nitrogen utilization
L	0030145	molecular_function	manganese ion binding
L	0046872	molecular_function	metal ion binding
L	0051260	biological_process	protein homooligomerization

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 469

Chain	Residue
A	GLU131
A	GLU212
A	GLU220
A	HOH5729
A	HOH5732

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 470

Chain	Residue
A	HOH5734
A	HOH5741
A	GLU129
A	HIS269
A	GLU357
A	ADP4471

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 469

Chain	Residue
B	GLU131
B	GLU212
B	GLU220
B	HOH5730
B	HOH5733

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 470

Chain	Residue
B	GLU129
B	HIS269
B	GLU357
B	ADP4472
B	HOH5735
B	HOH5742

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 469

Chain	Residue
C	GLU131
C	GLU212
C	GLU220
C	HOH5730
C	HOH5733

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN C 470

Chain	Residue
C	GLU129
C	HIS269
C	GLU357
C	ADP4473
C	HOH5735
C	HOH5742

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 469

Chain	Residue
D	GLU131
D	GLU212
D	GLU220
D	HOH1148
D	HOH1151

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN D 470

Chain	Residue
D	GLU129
D	HIS269
D	GLU357
D	HOH1153
D	HOH1160
D	ADP4474

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN E 469

Chain	Residue
E	GLU131
E	GLU212
E	GLU220
E	HOH1440
E	HOH1443

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 470

Chain	Residue
E	GLU129
E	HIS269
E	GLU357
E	HOH1445
E	HOH1452
E	ADP4475

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN F 469

Chain	Residue
F	GLU131
F	GLU212
F	GLU220
F	HOH5742
F	HOH5745

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 470

Chain	Residue
F	GLU129
F	HIS269
F	GLU357
F	ADP4476
F	HOH5747
F	HOH5754

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN G 469

Chain	Residue
G	GLU131
G	GLU212
G	GLU220
G	HOH5740
G	HOH5743

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN G 470

Chain	Residue
G	GLU129
G	HIS269
G	GLU357
G	ADP4477
G	HOH5745
G	HOH5752

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 469

Chain	Residue
H	GLU131
H	GLU212
H	GLU220
H	HOH5748
H	HOH5751

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN H 470

Chain	Residue
H	GLU129
H	HIS269
H	GLU357
H	ADP4478
H	HOH5753
H	HOH5760

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN I 469

Chain	Residue
I	GLU131
I	GLU212
I	GLU220
I	HOH5755
I	HOH5758

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN I 470

Chain	Residue
I	GLU129
I	HIS269
I	GLU357
I	ADP4479
I	HOH5760
I	HOH5767

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN J 469

Chain	Residue
J	GLU131
J	GLU212
J	GLU220
J	HOH2900
J	HOH2903

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN J 470

Chain	Residue
J	GLU129
J	HIS269
J	GLU357
J	HOH2905
J	HOH2912
J	ADP4480

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN K 469

Chain	Residue
K	GLU131
K	GLU212
K	GLU220
K	HOH3192
K	HOH3195

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN K 470

Chain	Residue
K	GLU129
K	HIS269
K	GLU357
K	HOH3197
K	HOH3204
K	ADP4481

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN L 469

Chain	Residue
L	GLU131
L	GLU212
L	GLU220
L	HOH3484
L	HOH3487

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN L 470

Chain	Residue
L	GLU129
L	HIS269
L	GLU357
L	HOH3489
L	HOH3496
L	ADP4482

site_id	CC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 4471

Chain	Residue
A	GLY127
A	GLU129
A	GLU207
A	THR223
A	ARG224
A	PHE225
A	HIS271
A	SER273
A	ARG344
A	ARG355
A	GLU357
A	MN470
A	HOH5727
A	HOH5734
A	HOH5741
A	HOH5753

site_id	CC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP B 4472

Chain	Residue
B	GLY127
B	GLU129
B	GLU207
B	THR223
B	ARG224
B	PHE225
B	HIS271
B	SER273
B	ARG344
B	ARG355
B	GLU357
B	MN470
B	HOH5728
B	HOH5735
B	HOH5742
B	HOH5756

site_id	CC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP C 4473

Chain	Residue
C	GLY127
C	GLU129
C	GLU207
C	THR223
C	ARG224
C	PHE225
C	HIS271
C	SER273
C	ARG344
C	ARG355
C	GLU357
C	MN470
C	HOH5728
C	HOH5735
C	HOH5742
C	HOH5756

site_id	DC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP D 4474

Chain	Residue
D	GLY127
D	GLU129
D	GLU207
D	THR223
D	ARG224
D	PHE225
D	HIS271
D	SER273
D	ARG344
D	ARG355
D	GLU357
D	MN470
D	HOH1146
D	HOH1153
D	HOH1160
D	HOH1372

site_id	DC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP E 4475

Chain	Residue
E	GLY127
E	GLU129
E	GLU207
E	THR223
E	ARG224
E	PHE225
E	HIS271
E	SER273
E	ARG344
E	ARG355
E	GLU357
E	MN470
E	HOH1438
E	HOH1445
E	HOH1452
E	HOH1664

site_id	DC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP F 4476

Chain	Residue
F	GLY127
F	GLU129
F	GLU207
F	THR223
F	ARG224
F	PHE225
F	HIS271
F	SER273
F	ARG344
F	ARG355
F	GLU357
F	MN470
F	HOH5487
F	HOH5740
F	HOH5747
F	HOH5754

site_id	DC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP G 4477

Chain	Residue
G	GLY127
G	GLU129
G	GLU207
G	THR223
G	ARG224
G	PHE225
G	HIS271
G	SER273
G	ARG344
G	ARG355
G	GLU357
G	MN470
G	HOH5738
G	HOH5745
G	HOH5752
G	HOH5772

site_id	DC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP H 4478

Chain	Residue
H	GLY127
H	GLU129
H	GLU207
H	THR223
H	ARG224
H	PHE225
H	HIS271
H	SER273
H	ARG344
H	ARG355
H	GLU357
H	MN470
H	HOH5504
H	HOH5746
H	HOH5753
H	HOH5760

site_id	DC6
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP I 4479

Chain	Residue
I	GLY127
I	GLU129
I	GLU207
I	THR223
I	ARG224
I	PHE225
I	HIS271
I	SER273
I	ARG344
I	ARG355
I	GLU357
I	MN470
I	HOH5506
I	HOH5753
I	HOH5760
I	HOH5767

site_id	DC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP J 4480

Chain	Residue
J	GLY127
J	GLU129
J	GLU207
J	THR223
J	ARG224
J	PHE225
J	HIS271
J	SER273
J	ARG344
J	ARG355
J	GLU357
J	MN470
J	HOH2540
J	HOH2898
J	HOH2905
J	HOH2912

site_id	DC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP K 4481

Chain	Residue
K	GLY127
K	GLU129
K	GLU207
K	THR223
K	ARG224
K	PHE225
K	HIS271
K	SER273
K	ARG344
K	ARG355
K	GLU357
K	MN470
K	HOH2832
K	HOH3190
K	HOH3197
K	HOH3204

site_id	DC9
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP L 4482

Chain	Residue
L	GLY127
L	GLU129
L	GLU207
L	THR223
L	ARG224
L	PHE225
L	HIS271
L	SER273
L	ARG344
L	ARG355
L	GLU357
L	MN470
L	HOH3124
L	HOH3482
L	HOH3489
L	HOH3496

site_id	EC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD B 5471

Chain	Residue
A	GLN189
A	ASP190
A	SER193
A	HIS209
B	PHE16
B	PHE80
B	ALA81
B	ASP82
B	THR84

site_id	EC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD A 5472

Chain	Residue
A	ARG20
A	PHE21
A	THR22
A	ARG88
A	CYS89
A	ASP90
A	ASP103
A	ARG105
A	ASP233
A	TYR368

site_id	EC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD C 5473

Chain	Residue
B	GLN189
B	ASP190
B	SER193
B	HIS209
C	PHE16
C	PHE80
C	ALA81
C	ASP82
C	THR84

site_id	EC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD B 5474

Chain	Residue
B	ARG20
B	PHE21
B	THR22
B	ARG88
B	CYS89
B	ASP90
B	ASP103
B	ARG105
B	ASP233
B	TYR368

site_id	EC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD D 5475

Chain	Residue
C	GLN189
C	ASP190
C	SER193
C	HIS209
D	PHE16
D	PHE80
D	ALA81
D	ASP82
D	THR84

site_id	EC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD C 5476

Chain	Residue
C	ARG20
C	PHE21
C	THR22
C	ARG88
C	CYS89
C	ASP90
C	ASP103
C	ARG105
C	ASP233
C	TYR368

site_id	EC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD E 5477

Chain	Residue
D	GLN189
D	ASP190
D	SER193
D	HIS209
E	PHE16
E	PHE80
E	ALA81
E	ASP82
E	THR84

site_id	EC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD D 5478

Chain	Residue
D	ARG20
D	PHE21
D	THR22
D	ARG88
D	CYS89
D	ASP90
D	ASP103
D	ARG105
D	ASP233
D	TYR368

site_id	EC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD F 5479

Chain	Residue
E	GLN189
E	ASP190
E	SER193
E	HIS209
F	PHE16
F	PHE80
F	ALA81
F	ASP82
F	THR84

site_id	FC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD E 5480

Chain	Residue
E	ARG20
E	PHE21
E	THR22
E	ARG88
E	CYS89
E	ASP90
E	ASP103
E	ARG105
E	ASP233
E	TYR368

site_id	FC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD A 5481

Chain	Residue
A	PHE16
A	PHE80
A	ALA81
A	ASP82
A	THR84
F	GLN189
F	ASP190
F	SER193
F	HIS209

site_id	FC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD F 5482

Chain	Residue
F	ARG20
F	PHE21
F	THR22
F	ARG88
F	CYS89
F	ASP90
F	ASP103
F	ARG105
F	ASP233
F	TYR368

site_id	FC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD L 5483

Chain	Residue
G	GLN189
G	ASP190
G	SER193
G	HIS209
L	PHE16
L	PHE80
L	ALA81
L	ASP82
L	THR84

site_id	FC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD G 5484

Chain	Residue
G	ARG20
G	PHE21
G	THR22
G	ARG88
G	CYS89
G	ASP90
G	ASP103
G	ARG105
G	ASP233
G	TYR368

site_id	FC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD G 5485

Chain	Residue
G	PHE16
G	PHE80
G	ALA81
G	ASP82
G	THR84
H	GLN189
H	ASP190
H	SER193
H	HIS209

site_id	FC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD H 5486

Chain	Residue
H	ARG20
H	PHE21
H	THR22
H	ARG88
H	CYS89
H	ASP90
H	ASP103
H	ARG105
H	ASP233
H	TYR368

site_id	FC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD H 5487

Chain	Residue
H	PHE16
H	PHE80
H	ALA81
H	ASP82
H	THR84
I	GLN189
I	ASP190
I	SER193
I	HIS209

site_id	FC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD I 5488

Chain	Residue
I	ARG20
I	PHE21
I	THR22
I	ARG88
I	CYS89
I	ASP90
I	ASP103
I	ARG105
I	ASP233
I	TYR368

site_id	GC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD I 5489

Chain	Residue
I	PHE16
I	PHE80
I	ALA81
I	ASP82
I	THR84
J	GLN189
J	ASP190
J	SER193
J	HIS209

site_id	GC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD J 5490

Chain	Residue
J	ARG20
J	PHE21
J	THR22
J	ARG88
J	CYS89
J	ASP90
J	ASP103
J	ARG105
J	ASP233
J	TYR368

site_id	GC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD J 5491

Chain	Residue
J	PHE16
J	PHE80
J	ALA81
J	ASP82
J	THR84
K	GLN189
K	ASP190
K	SER193
K	HIS209

site_id	GC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD K 5492

Chain	Residue
K	ARG20
K	PHE21
K	THR22
K	ARG88
K	CYS89
K	ASP90
K	ASP103
K	ARG105
K	ASP233
K	TYR368

site_id	GC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPD K 5493

Chain	Residue
K	PHE16
K	PHE80
K	ALA81
K	ASP82
K	THR84
L	GLN189
L	ASP190
L	SER193
L	HIS209

site_id	GC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPD L 5494

Chain	Residue
L	ARG20
L	PHE21
L	THR22
L	ARG88
L	CYS89
L	ASP90
L	ASP103
L	ARG105
L	ASP233
L	TYR368

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiggwkginESDmvL

Chain	Residue	Details
A	PHE49-LEU67

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMfgd..NGSGmHchmS

Chain	Residue	Details
A	LYS258-SER273

site_id	PS00182
Number of Residues	13
Details	GLNA_ADENYLATION Glutamine synthetase class-I adenylation site. KIhpgepMDKNLY

Chain	Residue	Details
A	LYS385-TYR397

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1008
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4368
Details	Domain: {"description":"GS catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01331","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2572586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12425","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P77961","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11329256","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2572586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7727369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1F1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1F52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FPY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8099447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2LGS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	12
Details	Modified residue: {"description":"O-AMP-tyrosine","evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
A	ARG339
A	ASP50
A	GLU327

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
B	ARG339
B	ASP50
B	GLU327

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
C	ARG339
C	ASP50
C	GLU327

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
D	ARG339
D	ASP50
D	GLU327

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
E	ARG339
E	ASP50
E	GLU327

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
F	ARG339
F	ASP50
F	GLU327

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
G	ARG339
G	ASP50
G	GLU327

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
H	ARG339
H	ASP50
H	GLU327

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
I	ARG339
I	ASP50
I	GLU327

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
J	ARG339
J	ASP50
J	GLU327

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
K	ARG339
K	ASP50
K	GLU327

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
L	ARG339
L	ASP50
L	GLU327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)