Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1F30

THE STRUCTURAL BASIS FOR DNA PROTECTION BY E. COLI DPS PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006950	biological_process	response to stress
A	0008199	molecular_function	ferric iron binding
A	0009295	cellular_component	nucleoid
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016722	molecular_function	oxidoreductase activity, acting on metal ions
A	0030261	biological_process	chromosome condensation
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042594	biological_process	response to starvation
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	1990084	cellular_component	DnaA-Dps complex
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006950	biological_process	response to stress
B	0008199	molecular_function	ferric iron binding
B	0009295	cellular_component	nucleoid
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016722	molecular_function	oxidoreductase activity, acting on metal ions
B	0030261	biological_process	chromosome condensation
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042594	biological_process	response to starvation
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	1990084	cellular_component	DnaA-Dps complex
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006950	biological_process	response to stress
C	0008199	molecular_function	ferric iron binding
C	0009295	cellular_component	nucleoid
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016722	molecular_function	oxidoreductase activity, acting on metal ions
C	0030261	biological_process	chromosome condensation
C	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
C	0042594	biological_process	response to starvation
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	1990084	cellular_component	DnaA-Dps complex
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006950	biological_process	response to stress
D	0008199	molecular_function	ferric iron binding
D	0009295	cellular_component	nucleoid
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016722	molecular_function	oxidoreductase activity, acting on metal ions
D	0030261	biological_process	chromosome condensation
D	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
D	0042594	biological_process	response to starvation
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	1990084	cellular_component	DnaA-Dps complex
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006950	biological_process	response to stress
E	0008199	molecular_function	ferric iron binding
E	0009295	cellular_component	nucleoid
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016722	molecular_function	oxidoreductase activity, acting on metal ions
E	0030261	biological_process	chromosome condensation
E	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
E	0042594	biological_process	response to starvation
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	1990084	cellular_component	DnaA-Dps complex
F	0003677	molecular_function	DNA binding
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006950	biological_process	response to stress
F	0008199	molecular_function	ferric iron binding
F	0009295	cellular_component	nucleoid
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016722	molecular_function	oxidoreductase activity, acting on metal ions
F	0030261	biological_process	chromosome condensation
F	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
F	0042594	biological_process	response to starvation
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	1990084	cellular_component	DnaA-Dps complex
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006950	biological_process	response to stress
G	0008199	molecular_function	ferric iron binding
G	0009295	cellular_component	nucleoid
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016722	molecular_function	oxidoreductase activity, acting on metal ions
G	0030261	biological_process	chromosome condensation
G	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
G	0042594	biological_process	response to starvation
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	1990084	cellular_component	DnaA-Dps complex
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006950	biological_process	response to stress
H	0008199	molecular_function	ferric iron binding
H	0009295	cellular_component	nucleoid
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0016722	molecular_function	oxidoreductase activity, acting on metal ions
H	0030261	biological_process	chromosome condensation
H	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
H	0042594	biological_process	response to starvation
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	1990084	cellular_component	DnaA-Dps complex
I	0003677	molecular_function	DNA binding
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006950	biological_process	response to stress
I	0008199	molecular_function	ferric iron binding
I	0009295	cellular_component	nucleoid
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0016722	molecular_function	oxidoreductase activity, acting on metal ions
I	0030261	biological_process	chromosome condensation
I	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
I	0042594	biological_process	response to starvation
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
I	1990084	cellular_component	DnaA-Dps complex
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006950	biological_process	response to stress
J	0008199	molecular_function	ferric iron binding
J	0009295	cellular_component	nucleoid
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0016722	molecular_function	oxidoreductase activity, acting on metal ions
J	0030261	biological_process	chromosome condensation
J	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
J	0042594	biological_process	response to starvation
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
J	1990084	cellular_component	DnaA-Dps complex
K	0003677	molecular_function	DNA binding
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006950	biological_process	response to stress
K	0008199	molecular_function	ferric iron binding
K	0009295	cellular_component	nucleoid
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0016722	molecular_function	oxidoreductase activity, acting on metal ions
K	0030261	biological_process	chromosome condensation
K	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
K	0042594	biological_process	response to starvation
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
K	1990084	cellular_component	DnaA-Dps complex
L	0003677	molecular_function	DNA binding
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006950	biological_process	response to stress
L	0008199	molecular_function	ferric iron binding
L	0009295	cellular_component	nucleoid
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0016722	molecular_function	oxidoreductase activity, acting on metal ions
L	0030261	biological_process	chromosome condensation
L	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
L	0042594	biological_process	response to starvation
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
L	1990084	cellular_component	DnaA-Dps complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 201

Chain	Residue
A	HIS51
A	HOH614
B	ASP78
B	GLU82

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	ASP78
A	GLU82
B	HIS51
B	HOH242
B	HOH247

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 201

Chain	Residue
C	HIS51
C	ASP78
C	GLU82
C	HOH645
C	HOH651

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN D 201

Chain	Residue
D	HIS51
D	HIS63
D	ASP78
D	GLU82
D	HOH454
D	HOH458

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 201

Chain	Residue
E	HIS51
E	HOH657
F	ASP78
F	GLU82

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 201

Chain	Residue
E	ASP78
E	GLU82
F	HIS51
F	HOH257

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN H 201

Chain	Residue
G	HIS51
H	ASP78
H	GLU82

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN G 201

Chain	Residue
G	ASP78
G	GLU82
H	HIS51
H	HIS63
H	HOH210

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN J 201

Chain	Residue
I	HIS51
I	HOH608
I	HOH611
J	ASP78
J	GLU82

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN I 201

Chain	Residue
I	ASP78
I	GLU82
J	HIS51
J	HOH622
J	HOH624

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN K 201

Chain	Residue
K	HIS51
K	ASP78
K	GLU82
K	HOH611
K	HOH613

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 201

Chain	Residue
H	HOH205
L	HIS51
L	ASP78
L	GLU82

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE TRS A 601

Chain	Residue
A	ALA57
A	GLU167
A	HOH655
D	ALA57
D	GLU167
E	ALA57
E	GLU167

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TRS A 602

Chain	Residue
A	GLU64
D	GLU64
D	HOH414
E	GLU64
E	HOH659
E	HOH663

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TRS E 603

Chain	Residue
B	ASP146
C	ASP146
E	ASP146

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TRS C 604

Chain	Residue
B	GLU64
B	HOH217
C	GLU64
C	HOH669
C	HOH672
F	GLU64

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TRS F 605

Chain	Residue
B	GLU167
C	GLU167
F	ALA57
F	GLU167
F	HOH168
F	HOH173

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TRS D 606

Chain	Residue
A	ASP146
A	HOH641
D	ASP146
F	ASP146

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TRS I 607

Chain	Residue
G	ASP146
I	ASP146
K	ASP146

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TRS L 608

Chain	Residue
H	GLU167
I	ALA57
I	GLU167
L	ALA57
L	GLU167

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE TRS L 609

Chain	Residue
I	GLU64
L	GLU64

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE TRS K 610

Chain	Residue
K	GLU64
G	GLU64
J	HOH616

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE TRS J 611

Chain	Residue
G	ALA57
G	GLU167
J	ALA57
J	GLU167
K	GLU167

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TRS J 612

Chain	Residue
H	ASP146
H	ALA150
J	ASP146
L	ASP146

Functional Information from PROSITE/UniProt

site_id	PS00818
Number of Residues	17
Details	DPS_1 Dps protein family signature 1. HWnMrGanfiaVHemlD

Chain	Residue	Details
A	HIS51-ASP67

site_id	PS00819
Number of Residues	15
Details	DPS_2 Dps protein family signature 2. LDtMAERavqLGgvA

Chain	Residue	Details
A	LEU77-ALA91

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"description":"in other chain"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)