1F07
STRUCTURE OF COENZYME F420 DEPENDENT TETRAHYDROMETHANOPTERIN REDUCTASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0015948 | biological_process | methanogenesis |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0018537 | molecular_function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity |
| A | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0015948 | biological_process | methanogenesis |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0018537 | molecular_function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity |
| B | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0015948 | biological_process | methanogenesis |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0018537 | molecular_function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity |
| C | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0015948 | biological_process | methanogenesis |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0018537 | molecular_function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity |
| D | 0019386 | biological_process | methanogenesis, from carbon dioxide |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 323 |
| Chain | Residue |
| C | ASN2041 |
| C | ARG2068 |
| D | ASN3041 |
| D | ARG3068 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 324 |
| Chain | Residue |
| A | ASN41 |
| A | ARG68 |
| B | ASN1041 |
| B | ARG1068 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MPO A 331 |
| Chain | Residue |
| A | THR34 |
| A | HIS36 |
| A | GLY61 |
| A | VAL62 |
| A | ASN171 |
| A | TYR204 |
| A | THR205 |
| A | ILE227 |
| A | SER301 |
| A | HOH456 |
| A | HOH475 |
| A | HOH785 |
| A | GLU6 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MPO B 332 |
| Chain | Residue |
| B | HOH449 |
| B | HOH461 |
| B | HOH882 |
| B | GLU1006 |
| B | THR1034 |
| B | HIS1036 |
| B | GLY1061 |
| B | VAL1062 |
| B | ASN1171 |
| B | TYR1204 |
| B | THR1205 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MPO C 333 |
| Chain | Residue |
| C | HOH361 |
| C | HOH384 |
| C | HOH587 |
| C | HOH729 |
| C | HOH826 |
| C | GLU2006 |
| C | HIS2036 |
| C | GLY2061 |
| C | VAL2062 |
| C | ASN2171 |
| C | TYR2204 |
| C | THR2205 |
| C | ILE2227 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MPO D 334 |
| Chain | Residue |
| D | HOH403 |
| D | HOH405 |
| D | HOH883 |
| D | GLU3006 |
| D | THR3034 |
| D | HIS3036 |
| D | GLY3061 |
| D | VAL3062 |
| D | ASN3171 |
| D | TYR3204 |
| D | THR3205 |
| D | ILE3227 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 335 |
| Chain | Residue |
| A | PRO155 |
| A | ILE170 |
| A | ALA180 |
| A | ARG238 |
| A | HOH584 |
| A | HOH798 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 336 |
| Chain | Residue |
| B | GLN1153 |
| B | GLY1154 |
| B | PRO1155 |
| B | ILE1170 |
| B | LEU1184 |
| B | ARG1238 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD C 337 |
| Chain | Residue |
| C | HOH482 |
| C | HOH800 |
| C | GLN2153 |
| C | PRO2155 |
| C | ILE2170 |
| C | ALA2180 |
| C | VAL2235 |
| C | ARG2238 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD D 338 |
| Chain | Residue |
| D | LEU3158 |
| D | ALA3181 |
| D | LEU3184 |
| D | ARG3238 |
