1EYR
Structure of a sialic acid activating synthetase, CMP acylneuraminate synthetase in the presence and absence of CDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008781 | molecular_function | N-acylneuraminate cytidylyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008781 | molecular_function | N-acylneuraminate cytidylyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CDP A 1001 |
| Chain | Residue |
| A | LEU10 |
| A | PRO105 |
| A | THR106 |
| A | ASP209 |
| A | ILE210 |
| A | ASP211 |
| A | HOH1010 |
| A | HOH1054 |
| A | HOH1091 |
| A | HOH1242 |
| A | HOH1243 |
| A | ALA11 |
| A | ARG12 |
| A | SER15 |
| A | LYS21 |
| A | ASN22 |
| A | ARG71 |
| A | ALA80 |
| A | SER82 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE CDP B 2001 |
| Chain | Residue |
| B | LEU10 |
| B | ALA11 |
| B | ARG12 |
| B | SER15 |
| B | LYS16 |
| B | LYS21 |
| B | ASN22 |
| B | ARG71 |
| B | ALA80 |
| B | SER82 |
| B | PRO105 |
| B | THR106 |
| B | ASP209 |
| B | ILE210 |
| B | ASP211 |
| B | HOH2018 |
| B | HOH2055 |
| B | HOH2076 |
| B | HOH2101 |
| B | HOH2173 |
| B | HOH2208 |
| B | HOH2209 |
