1EXP

BETA-1,4-GLYCANASE CEX-CD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process

Functional Information from PDB Data

site_id	ABC
Number of Residues	1
Details	ACID BASE CATALYST.

Chain	Residue
A	GLU127

---

site_id	NUC
Number of Residues	1
Details	CATALYTIC NUCLEOPHILE, COVALENTLY LINKED TO THE FLUOROCELLOBIOSIDE.

Chain	Residue
A	GLU233

---

Functional Information from PROSITE/UniProt

site_id	PS00591
Number of Residues	11
Details	GH10_1 Glycosyl hydrolases family 10 (GH10) active site. GVDVrITELDI

Chain	Residue	Details
A	GLY226-ILE236

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	310
Details	Domain: {"description":"GH10","evidences":[{"source":"PROSITE-ProRule","id":"PRU01096","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"7918478","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10061","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1678739","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	a catalytic site defined by CSA, PubMed 8564541, 19279191

Chain	Residue	Details
A	GLU233
A	GLU127
A	ASN169
A	HIS205
A	ASP235

---

site_id	MCSA1
Number of Residues	5
Details	M-CSA 548

Chain	Residue	Details
A	GLU127	proton acceptor, proton donor
A	ASN169	electrostatic stabiliser
A	HIS205	electrostatic stabiliser
A	GLU233	electrostatic stabiliser, nucleofuge, nucleophile
A	ASP235	electrostatic stabiliser

---