1ETE

CRYSTAL STRUCTURE OF THE FLT3 LIGAND

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0016020	cellular_component	membrane
B	0005125	molecular_function	cytokine activity
B	0016020	cellular_component	membrane
C	0005125	molecular_function	cytokine activity
C	0016020	cellular_component	membrane
D	0005125	molecular_function	cytokine activity
D	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 135

Chain	Residue
A	GLU58
A	HIS80
A	HOH4067
A	HOH4068

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 136

Chain	Residue
A	HIS8
C	GLU129

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 137

Chain	Residue
A	ASP3
C	ASP3

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 1135

Chain	Residue
B	GLU110
B	HIS80

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1136

Chain	Residue
B	SER12
B	ASP14
B	LYS18
B	GLU78

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 1137

Chain	Residue
B	GLN2
B	ASP40
B	GLU42
B	HOH5017
C	HIS8

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C 2135

Chain	Residue
C	GLU58
C	HIS80
C	HOH6033

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site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN C 2136

Chain	Residue
B	PRO134
C	SER12
C	ASP14
C	LYS18
C	GLU78
C	HOH6042

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN D 3135

Chain	Residue
D	GLU58
D	HIS80

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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