Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006413 | biological_process | translational initiation |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003743 | molecular_function | translation initiation factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006413 | biological_process | translational initiation |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003743 | molecular_function | translation initiation factor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006413 | biological_process | translational initiation |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003743 | molecular_function | translation initiation factor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006413 | biological_process | translational initiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE M7G A 1001 |
| Chain | Residue |
| A | TRP56 |
| A | MET101 |
| A | TRP102 |
| A | GLU103 |
| A | ARG157 |
| A | LYS162 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE M7G B 1002 |
| Chain | Residue |
| B | GLU103 |
| B | ARG157 |
| B | LYS162 |
| B | TRP56 |
| B | MET101 |
| B | TRP102 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE M7G C 1003 |
| Chain | Residue |
| C | TRP56 |
| C | MET101 |
| C | TRP102 |
| C | GLU103 |
| C | ARG157 |
| C | LYS162 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE M7G D 1004 |
| Chain | Residue |
| D | TRP56 |
| D | MET101 |
| D | TRP102 |
| D | GLU103 |
| D | ARG157 |
| D | LYS162 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKdgIePmWEDeknkrGGRW |
| Chain | Residue | Details |
| A | ASP90-TRP113 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| E | TYR624 | |
| C | TRP102 | |
| C | ARG157 | |
| C | THR205 | |
| D | TRP56 | |
| D | TRP102 | |
| D | ARG157 | |
| D | THR205 | |
| F | TYR624 | |
| G | TYR624 | |
| H | TYR624 | |
| B | TRP56 | |
| B | TRP102 | |
| B | ARG157 | |
| B | THR205 | |
| C | TRP56 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by DYRK2, MAPK1, MAPK3 and MTOR => ECO:0000269|PubMed:12588975, ECO:0000269|PubMed:12747827, ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:25702871, ECO:0000269|PubMed:29750193, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| E | MET635 | |
| F | MET635 | |
| G | MET635 | |
| H | MET635 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:22578813 |
| Chain | Residue | Details |
| E | GLU627 | |
| F | GLU627 | |
| G | GLU627 | |
| H | GLU627 | |
