1EJB
LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0009349 | cellular_component | riboflavin synthase complex |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005758 | cellular_component | mitochondrial intermembrane space |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0009349 | cellular_component | riboflavin synthase complex |
| B | 0016740 | molecular_function | transferase activity |
| C | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005758 | cellular_component | mitochondrial intermembrane space |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0009349 | cellular_component | riboflavin synthase complex |
| C | 0016740 | molecular_function | transferase activity |
| D | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005758 | cellular_component | mitochondrial intermembrane space |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0009349 | cellular_component | riboflavin synthase complex |
| D | 0016740 | molecular_function | transferase activity |
| E | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| E | 0005634 | cellular_component | nucleus |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005758 | cellular_component | mitochondrial intermembrane space |
| E | 0009231 | biological_process | riboflavin biosynthetic process |
| E | 0009349 | cellular_component | riboflavin synthase complex |
| E | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE INJ A 200 |
| Chain | Residue |
| A | TRP26 |
| A | GLY93 |
| A | SER94 |
| A | THR95 |
| A | ILE101 |
| A | HOH205 |
| A | HOH221 |
| A | HOH295 |
| A | HOH296 |
| A | HOH297 |
| B | ILE121 |
| A | ASN27 |
| B | PHE122 |
| B | ARG136 |
| B | TRP152 |
| A | GLY59 |
| A | SER60 |
| A | TYR61 |
| A | GLU62 |
| A | VAL89 |
| A | LEU90 |
| A | ILE91 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE INJ B 300 |
| Chain | Residue |
| B | TRP26 |
| B | ASN27 |
| B | GLY59 |
| B | SER60 |
| B | TYR61 |
| B | GLU62 |
| B | VAL89 |
| B | LEU90 |
| B | ILE91 |
| B | GLY93 |
| B | SER94 |
| B | THR95 |
| B | ILE101 |
| B | HOH320 |
| B | HOH336 |
| B | HOH398 |
| B | HOH401 |
| B | HOH407 |
| B | HOH408 |
| B | HOH409 |
| C | ILE121 |
| C | PHE122 |
| C | ARG136 |
| C | TRP152 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE INJ C 400 |
| Chain | Residue |
| C | TRP26 |
| C | GLY59 |
| C | SER60 |
| C | TYR61 |
| C | GLU62 |
| C | VAL89 |
| C | LEU90 |
| C | ILE91 |
| C | GLY93 |
| C | SER94 |
| C | THR95 |
| C | ILE101 |
| C | HOH409 |
| C | HOH434 |
| C | HOH483 |
| C | HOH1310 |
| C | HOH1356 |
| C | HOH1378 |
| D | ILE121 |
| D | PHE122 |
| D | ARG136 |
| D | TRP152 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE INJ D 600 |
| Chain | Residue |
| D | TRP26 |
| D | GLY59 |
| D | SER60 |
| D | TYR61 |
| D | GLU62 |
| D | VAL89 |
| D | LEU90 |
| D | ILE91 |
| D | GLY93 |
| D | SER94 |
| D | THR95 |
| D | ILE101 |
| D | HOH609 |
| D | HOH634 |
| D | HOH683 |
| D | HOH890 |
| D | HOH1510 |
| D | HOH1529 |
| D | HOH1556 |
| D | HOH1578 |
| E | ILE121 |
| E | PHE122 |
| E | ARG136 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE INJ E 800 |
| Chain | Residue |
| E | SER60 |
| E | TYR61 |
| E | GLU62 |
| E | VAL89 |
| E | LEU90 |
| E | ILE91 |
| E | GLY93 |
| E | SER94 |
| E | THR95 |
| E | HOH804 |
| E | HOH807 |
| E | HOH824 |
| E | HOH840 |
| E | HOH877 |
| E | HOH911 |
| E | HOH912 |
| E | HOH913 |
| A | ILE121 |
| A | PHE122 |
| A | ARG136 |
| A | TRP152 |
| A | HOH300 |
| E | TRP26 |
| E | ASN27 |
| E | GLY59 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS97 | |
| B | HIS97 | |
| C | HIS97 | |
| D | HIS97 | |
| E | HIS97 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | TRP26 | |
| B | SER94 | |
| B | PHE122 | |
| B | ARG136 | |
| C | TRP26 | |
| C | SER60 | |
| C | VAL89 | |
| C | SER94 | |
| C | PHE122 | |
| C | ARG136 | |
| D | TRP26 | |
| A | SER60 | |
| D | SER60 | |
| D | VAL89 | |
| D | SER94 | |
| D | PHE122 | |
| D | ARG136 | |
| E | TRP26 | |
| E | SER60 | |
| E | VAL89 | |
| E | SER94 | |
| E | PHE122 | |
| A | VAL89 | |
| E | ARG136 | |
| A | SER94 | |
| A | PHE122 | |
| A | ARG136 | |
| B | TRP26 | |
| B | SER60 | |
| B | VAL89 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| A | HIS97 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| B | HIS97 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| C | HIS97 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| D | HIS97 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| E | HIS97 |
