1EJ6
Reovirus core
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004482 | molecular_function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity |
| A | 0004484 | molecular_function | mRNA guanylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| A | 0006397 | biological_process | mRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019028 | cellular_component | viral capsid |
| A | 0019030 | cellular_component | icosahedral viral capsid |
| A | 0032259 | biological_process | methylation |
| A | 0039624 | cellular_component | viral outer capsid |
| A | 0044423 | cellular_component | virion component |
| A | 0106005 | biological_process | RNA 5'-cap (guanine-N7)-methylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003724 | molecular_function | RNA helicase activity |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| B | 0006397 | biological_process | mRNA processing |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0019028 | cellular_component | viral capsid |
| B | 0039616 | cellular_component | T=2 icosahedral viral capsid |
| B | 0039625 | cellular_component | viral inner capsid |
| B | 0044423 | cellular_component | virion component |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003724 | molecular_function | RNA helicase activity |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006370 | biological_process | 7-methylguanosine mRNA capping |
| C | 0006397 | biological_process | mRNA processing |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0019028 | cellular_component | viral capsid |
| C | 0039616 | cellular_component | T=2 icosahedral viral capsid |
| C | 0039625 | cellular_component | viral inner capsid |
| C | 0044423 | cellular_component | virion component |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0019028 | cellular_component | viral capsid |
| D | 0039625 | cellular_component | viral inner capsid |
| D | 0044423 | cellular_component | virion component |
| E | 0019028 | cellular_component | viral capsid |
| E | 0039625 | cellular_component | viral inner capsid |
| E | 0044423 | cellular_component | virion component |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 2000 |
| Chain | Residue |
| C | CYS183 |
| C | CYS186 |
| C | HIS199 |
| C | HIS203 |
Functional Information from PROSITE/UniProt
| site_id | PS00028 |
| Number of Residues | 21 |
| Details | ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Chv..CsavLfspldldaHvas..H |
| Chain | Residue | Details |
| B | CYS183-HIS203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 257 |
| Details | Region: {"description":"Probable N7-modifying activity","evidences":[{"source":"PubMed","id":"10801118","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 218 |
| Details | Region: {"description":"Probable O-methyltransferase activity","evidences":[{"source":"PubMed","id":"10801118","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Contributes to the autoguanylylation","evidences":[{"source":"PubMed","id":"10644745","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in formation of the phosphoamide bond (autoguanylation)","evidences":[{"source":"PubMed","id":"10644745","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | Zinc finger: {"description":"C2H2-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 11 |
| Details | Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 42 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 31 |
| Details | Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
