1EGA
CRYSTAL STRUCTURE OF A WIDELY CONSERVED GTPASE ERA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000028 | biological_process | ribosomal small subunit assembly |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| A | 0019843 | molecular_function | rRNA binding |
| A | 0042254 | biological_process | ribosome biogenesis |
| A | 0042274 | biological_process | ribosomal small subunit biogenesis |
| A | 0043024 | molecular_function | ribosomal small subunit binding |
| A | 0046777 | biological_process | protein autophosphorylation |
| A | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0000028 | biological_process | ribosomal small subunit assembly |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| B | 0019843 | molecular_function | rRNA binding |
| B | 0042254 | biological_process | ribosome biogenesis |
| B | 0042274 | biological_process | ribosomal small subunit biogenesis |
| B | 0043024 | molecular_function | ribosomal small subunit binding |
| B | 0046777 | biological_process | protein autophosphorylation |
| B | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ASN18 |
| A | VAL19 |
| A | GLY20 |
| A | LYS21 |
| A | SER22 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | THR23 |
| A | ASN26 |
| A | LYS27 |
| A | THR36 |
| A | THR215 |
| A | LYS282 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| B | ASN18 |
| B | VAL19 |
| B | GLY20 |
| B | LYS21 |
| B | SER22 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 304 |
| Chain | Residue |
| B | THR23 |
| B | ASN26 |
| B | LYS27 |
| B | THR36 |
| B | THR215 |
| B | LYS282 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | LYS32 |
| A | TYR212 |
| A | HOH374 |
| A | HOH405 |
| site_id | HG |
| Number of Residues | 4 |
| Details | MERCURY ATOM-BINDING SITES IN EMP DERIVATIVE USED IN MAD PHASING |
| Chain | Residue |
| A | CYS8 |
| A | HIS51 |
| B | CYS8 |
| B | HIS51 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 336 |
| Details | Domain: {"description":"Era-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 154 |
| Details | Domain: {"description":"KH type-2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01050","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"3097637","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"8057845","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"8057845","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | ASP62 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | ASP62 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | LEU66 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | LEU66 |
