1EDZ

STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004487	molecular_function	methylenetetrahydrofolate dehydrogenase (NAD+) activity
A	0004488	molecular_function	methylenetetrahydrofolate dehydrogenase (NADP+) activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006730	biological_process	one-carbon metabolic process
A	0009113	biological_process	purine nucleobase biosynthetic process
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	CYS150

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:10933503

Chain	Residue	Details
A	ARG185
A	ASP208
A	PHE274

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1a4i

Chain	Residue	Details
A	THR57

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