1E6C
K15M MUTANT OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004765 | molecular_function | shikimate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004765 | molecular_function | shikimate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 802 |
| Chain | Residue |
| A | ARG11 |
| A | GLY12 |
| A | GLY14 |
| A | MET15 |
| A | THR16 |
| A | HOH2007 |
| A | HOH2011 |
| A | HOH2111 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 804 |
| Chain | Residue |
| A | GLY79 |
| A | ARG139 |
| A | MRD903 |
| A | ARG11 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 801 |
| Chain | Residue |
| B | ARG11 |
| B | GLY12 |
| B | GLY14 |
| B | MET15 |
| B | THR16 |
| B | HOH2005 |
| B | HOH2101 |
| B | HOH2102 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 803 |
| Chain | Residue |
| B | ARG11 |
| B | GLY79 |
| B | ARG139 |
| B | MPD901 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MRD A 903 |
| Chain | Residue |
| A | ALA10 |
| A | LEU107 |
| A | ARG110 |
| A | ARG139 |
| A | CL804 |
| A | HOH2008 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 902 |
| Chain | Residue |
| A | SER41 |
| A | GLY42 |
| A | THR44 |
| A | VAL45 |
| A | PHE57 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 906 |
| Chain | Residue |
| A | ALA108 |
| A | GLN112 |
| A | ILE128 |
| A | ALA129 |
| A | MET132 |
| A | HOH2089 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 901 |
| Chain | Residue |
| B | ALA10 |
| B | LEU107 |
| B | ARG110 |
| B | ARG139 |
| B | CL803 |
| B | HOH2103 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD B 904 |
| Chain | Residue |
| B | GLN38 |
| B | SER41 |
| B | GLY42 |
| B | MET43 |
| B | THR44 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 905 |
| Chain | Residue |
| B | GLN112 |
| B | LEU115 |
| B | GLN116 |
| B | MET132 |
Functional Information from PROSITE/UniProt
| site_id | PS01128 |
| Number of Residues | 25 |
| Details | SHIKIMATE_KINASE Shikimate kinase signature. RrrEseaLqavatpnr....VVAtGGGmV |
| Chain | Residue | Details |
| A | ARG58-VAL82 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP32 | |
| A | GLN155 | |
| B | GLY12 | |
| B | THR16 | |
| B | ASP32 | |
| B | GLN155 | |
| A | GLY12 | |
| A | THR16 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| B | ARG58 | |
| B | ARG139 | |
| A | ASP34 | |
| A | ARG58 | |
| A | ARG139 | |
| B | ASP34 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY79 | |
| A | ARG120 | |
| B | GLY79 | |
| B | ARG120 |
