1E2X
FadR, fatty acid responsive transcription factor from E. coli
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000062 | molecular_function | fatty-acyl-CoA binding |
A | 0003677 | molecular_function | DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0006631 | biological_process | fatty acid metabolic process |
A | 0019217 | biological_process | regulation of fatty acid metabolic process |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0045723 | biological_process | positive regulation of fatty acid biosynthetic process |
A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A4001 |
Chain | Residue |
A | ARG114 |
A | THR115 |
A | ARG118 |
A | GLN119 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A4002 |
Chain | Residue |
A | GLY79 |
A | ASN81 |
A | HOH2155 |
A | HOH2156 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 19 |
Details | DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00696 |
Chain | Residue | Details |
A | ARG35-ARG54 |
site_id | SWS_FT_FI2 |
Number of Residues | 35 |
Details | DNA_BIND: H-T-H motif => ECO:0000269|PubMed:11279025, ECO:0000269|PubMed:11296236 |
Chain | Residue | Details |
A | ARG35-LYS70 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:11296236 |
Chain | Residue | Details |
A | ASN100 | |
A | VAL104 | |
A | ARG214 | |
A | GLY220 |