1E12

Halorhodopsin, a light-driven chloride pump

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0007602	biological_process	phototransduction
A	0009881	molecular_function	photoreceptor activity
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 501

Chain	Residue
A	THR111
A	SER115
A	LYS242

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K A 503

Chain	Residue
A	GLY83
A	VAL86

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE RET A 999

Chain	Residue
A	SER168
A	PHE172
A	TRP207
A	TYR210
A	PRO211
A	ASP238
A	LYS242
A	TRP112
A	THR116
A	MET144
A	TYR165

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PLM A 700

Chain	Residue
A	SER75
A	LEU110
A	THR111
A	PRO117
A	PHE135
A	ALA139
A	VAL146

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE OLC A 701

Chain	Residue
A	TRP162
A	HOH2064

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE OLC A 703

Chain	Residue
A	OLC705
A	OLC719

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE OLC A 705

Chain	Residue
A	OLC703

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE OLC A 709

Chain	Residue
A	ALA157
A	LEU159
A	PHE160
A	OLC717

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE OLC A 711

Chain	Residue
A	ILE212

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE OLC A 713

Chain	Residue
A	GLY41
A	ILE42
A	LEU45
A	OLC715

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE OLC A 715

Chain	Residue
A	VAL37
A	ALA38
A	LEU45
A	OLC713
A	OLC717

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OLC A 717

Chain	Residue
A	ARG52
A	OLC709
A	OLC715

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE OLC A 719

Chain	Residue
A	OLC703

---

Functional Information from PROSITE/UniProt

site_id	PS00327
Number of Residues	12
Details	BACTERIAL_OPSIN_RET Bacterial rhodopsins retinal binding site. YSVLDVfAKyVF

Chain	Residue	Details
A	TYR234-PHE245

---

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYlTWaLSTPMIL

Chain	Residue	Details
A	ARG108-LEU120

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	TOPO_DOM: Extracellular => ECO:0000250

Chain	Residue	Details
A	ALA22-GLU25
A	SER82-GLN105
A	THR155-ALA157
A	GLY217-SER226

---

site_id	SWS_FT_FI2
Number of Residues	25
Details	TRANSMEM: Helical; Name=Helix A => ECO:0000250

Chain	Residue	Details
A	ASN26-GLY51

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	TOPO_DOM: Cytoplasmic => ECO:0000250

Chain	Residue	Details
A	ARG52-GLY57
A	ASP128-ASP130
A	THR181-THR192
A	ASN256-ASP274

---

site_id	SWS_FT_FI4
Number of Residues	23
Details	TRANSMEM: Helical; Name=Helix B => ECO:0000250

Chain	Residue	Details
A	ARG58-LEU81

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	TRANSMEM: Helical; Name=Helix C => ECO:0000250

Chain	Residue	Details
A	TRP106-ALA127

---

site_id	SWS_FT_FI6
Number of Residues	23
Details	TRANSMEM: Helical; Name=Helix D => ECO:0000250

Chain	Residue	Details
A	LEU131-THR154

---

site_id	SWS_FT_FI7
Number of Residues	22
Details	TRANSMEM: Helical; Name=Helix E => ECO:0000250

Chain	Residue	Details
A	LEU158-VAL180

---

site_id	SWS_FT_FI8
Number of Residues	23
Details	TRANSMEM: Helical; Name=Helix F => ECO:0000250

Chain	Residue	Details
A	ALA193-VAL216

---

site_id	SWS_FT_FI9
Number of Residues	28
Details	TRANSMEM: Helical; Name=Helix G => ECO:0000250

Chain	Residue	Details
A	VAL227-ASN255

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: N6-(retinylidene)lysine => ECO:0000250

Chain	Residue	Details
A	LYS242

---