1DU3
Crystal structure of TRAIL-SDR5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0045569 | molecular_function | TRAIL binding |
| B | 0045569 | molecular_function | TRAIL binding |
| C | 0045569 | molecular_function | TRAIL binding |
| D | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| D | 0006955 | biological_process | immune response |
| D | 0016020 | cellular_component | membrane |
| E | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| E | 0006955 | biological_process | immune response |
| E | 0016020 | cellular_component | membrane |
| F | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| F | 0006955 | biological_process | immune response |
| F | 0016020 | cellular_component | membrane |
| G | 0045569 | molecular_function | TRAIL binding |
| H | 0045569 | molecular_function | TRAIL binding |
| I | 0045569 | molecular_function | TRAIL binding |
| J | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| J | 0006955 | biological_process | immune response |
| J | 0016020 | cellular_component | membrane |
| K | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| K | 0006955 | biological_process | immune response |
| K | 0016020 | cellular_component | membrane |
| L | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| L | 0006955 | biological_process | immune response |
| L | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 1 |
| Chain | Residue |
| D | CYS230 |
| E | CYS230 |
| E | HOH3113 |
| F | CYS230 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN K 2 |
| Chain | Residue |
| J | CYS230 |
| K | CYS230 |
| K | HOH3107 |
| L | CYS230 |
Functional Information from PROSITE/UniProt
| site_id | PS00251 |
| Number of Residues | 17 |
| Details | THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvIHeKGFYYIysQTyF |
| Chain | Residue | Details |
| D | LEU174-PHE190 |
| site_id | PS00652 |
| Number of Residues | 41 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ckygqd.Ysthwndllf.ClrCtr.Cdsgevelsp..Ctttr..NTVC |
| Chain | Residue | Details |
| A | CYS44-CYS84 | |
| A | CYS84-CYS125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10549288","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26457518","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CIR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
