1DU3

Crystal structure of TRAIL-SDR5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0045569	molecular_function	TRAIL binding
B	0045569	molecular_function	TRAIL binding
C	0045569	molecular_function	TRAIL binding
D	0005164	molecular_function	tumor necrosis factor receptor binding
D	0006955	biological_process	immune response
D	0016020	cellular_component	membrane
E	0005164	molecular_function	tumor necrosis factor receptor binding
E	0006955	biological_process	immune response
E	0016020	cellular_component	membrane
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0006955	biological_process	immune response
F	0016020	cellular_component	membrane
G	0045569	molecular_function	TRAIL binding
H	0045569	molecular_function	TRAIL binding
I	0045569	molecular_function	TRAIL binding
J	0005164	molecular_function	tumor necrosis factor receptor binding
J	0006955	biological_process	immune response
J	0016020	cellular_component	membrane
K	0005164	molecular_function	tumor necrosis factor receptor binding
K	0006955	biological_process	immune response
K	0016020	cellular_component	membrane
L	0005164	molecular_function	tumor necrosis factor receptor binding
L	0006955	biological_process	immune response
L	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 1

Chain	Residue
D	CYS230
E	CYS230
E	HOH3113
F	CYS230

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 2

Chain	Residue
J	CYS230
K	CYS230
K	HOH3107
L	CYS230

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Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvIHeKGFYYIysQTyF

Chain	Residue	Details
D	LEU174-PHE190

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site_id	PS00652
Number of Residues	41
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ckygqd.Ysthwndllf.ClrCtr.Cdsgevelsp..Ctttr..NTVC

Chain	Residue	Details
A	CYS44-CYS84
A	CYS84-CYS125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:10549288, ECO:0000269|PubMed:26457518, ECO:0007744|PDB:5CIR

Chain	Residue	Details
D	CYS230
E	CYS230
F	CYS230
J	CYS230
K	CYS230
L	CYS230

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