1DKS
CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 IN COMPLEX WITH PHOSPHATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000307 | cellular_component | cyclin-dependent protein kinase holoenzyme complex |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
| A | 0019005 | cellular_component | SCF ubiquitin ligase complex |
| A | 0044772 | biological_process | mitotic cell cycle phase transition |
| A | 0061575 | molecular_function | cyclin-dependent protein serine/threonine kinase activator activity |
| B | 0000307 | cellular_component | cyclin-dependent protein kinase holoenzyme complex |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
| B | 0019005 | cellular_component | SCF ubiquitin ligase complex |
| B | 0044772 | biological_process | mitotic cell cycle phase transition |
| B | 0061575 | molecular_function | cyclin-dependent protein serine/threonine kinase activator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 300 |
| Chain | Residue |
| A | PO4400 |
| B | LYS11 |
| B | ARG20 |
| B | GLN50 |
| B | SER51 |
| B | TRP54 |
| B | HOH965 |
| B | HOH966 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 400 |
| Chain | Residue |
| A | LYS11 |
| A | ARG20 |
| A | GLN50 |
| A | SER51 |
| A | TRP54 |
| A | ARG71 |
| A | HOH907 |
| B | PO4300 |
| B | HOH966 |
| site_id | POA |
| Number of Residues | 5 |
| Details |
| Chain | Residue |
| A | LYS11 |
| A | ARG20 |
| A | SER51 |
| A | TRP54 |
| A | ARG71 |
| site_id | POB |
| Number of Residues | 5 |
| Details |
| Chain | Residue |
| B | ARG71 |
| B | LYS11 |
| B | ARG20 |
| B | SER51 |
| B | TRP54 |
Functional Information from PROSITE/UniProt
| site_id | PS00944 |
| Number of Residues | 19 |
| Details | CKS_1 Cyclin-dependent kinases regulatory subunits signature 1. YSdKYdDEeFEYRHVmLPK |
| Chain | Residue | Details |
| A | TYR8-LYS26 |
| site_id | PS00945 |
| Number of Residues | 11 |
| Details | CKS_2 Cyclin-dependent kinases regulatory subunits signature 2. HePEpHILLFR |
| Chain | Residue | Details |
| A | HIS60-ARG70 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
