1DJ7
CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0015979 | biological_process | photosynthesis |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016730 | molecular_function | oxidoreductase activity, acting on iron-sulfur proteins as donors |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0103012 | molecular_function | ferredoxin-thioredoxin reductase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0015979 | biological_process | photosynthesis |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| A | ARG80 |
| B | LYS62 |
| B | HIS64 |
| B | HOH204 |
| B | HOH216 |
| B | HOH236 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 A 120 |
| Chain | Residue |
| A | MET79 |
| A | CYS85 |
| A | HIS86 |
| A | CYS87 |
| A | CYS55 |
| A | CYS74 |
| A | CYS76 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:10649999, ECO:0000269|PubMed:14769790, ECO:0000269|PubMed:17611542, ECO:0000269|PubMed:19132843 |
| Chain | Residue | Details |
| A | CYS57 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10649999, ECO:0000269|PubMed:17611542 |
| Chain | Residue | Details |
| A | CYS55 | |
| A | CYS74 | |
| A | CYS76 | |
| A | CYS85 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Increases the nucleophilicity of the active site Cys => ECO:0000269|PubMed:19132843 |
| Chain | Residue | Details |
| A | HIS86 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 980 |
| Chain | Residue | Details |
| A | CYS55 | electrofuge, electrophile, hydrogen bond acceptor, metal ligand |
| A | CYS57 | electrofuge, electrophile, metal ligand, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | CYS74 | metal ligand |
| A | CYS76 | metal ligand |
| A | CYS85 | metal ligand |
| A | HIS86 | electrostatic stabiliser, proton donor |
| A | CYS87 | activator, covalent catalysis, electrofuge, electrophile, hydrogen bond donor, metal ligand, nucleofuge, nucleophile, proton acceptor, proton donor |
