Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003993 | molecular_function | acid phosphatase activity |
A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0004726 | molecular_function | non-membrane spanning protein tyrosine phosphatase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016791 | molecular_function | phosphatase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE EPE A 201 |
Chain | Residue |
A | CYS12 |
A | TYR132 |
A | LEU13 |
A | GLY14 |
A | ASN15 |
A | ILE16 |
A | CYS17 |
A | ARG18 |
A | ASP129 |
A | TYR131 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LEU13 | |
Chain | Residue | Details |
A | SER19 | |
Chain | Residue | Details |
A | PRO130 | |
Chain | Residue | Details |
A | TYR132 | |
A | GLY133 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1pnt |
Chain | Residue | Details |
A | CYS17 | |
A | ARG18 | |
A | ASP129 | |
A | CYS12 | |
site_id | MCSA1 |
Number of Residues | 6 |
Details | M-CSA 462 |
Chain | Residue | Details |
A | LEU13 | covalent catalysis |
A | ILE16 | activator, electrostatic stabiliser |
A | ARG18 | steric role |
A | SER19 | transition state stabiliser |
A | PRO20 | activator, electrostatic stabiliser |
A | PRO130 | proton shuttle (general acid/base) |