1DG1

WHOLE, UNMODIFIED, EF-TU(ELONGATION FACTOR TU).

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0000287	molecular_function	magnesium ion binding
G	0003746	molecular_function	translation elongation factor activity
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005737	cellular_component	cytoplasm
G	0005886	cellular_component	plasma membrane
G	0006414	biological_process	translational elongation
G	0032045	cellular_component	guanyl-nucleotide exchange factor complex
G	0097216	molecular_function	guanosine tetraphosphate binding
H	0000287	molecular_function	magnesium ion binding
H	0003746	molecular_function	translation elongation factor activity
H	0003924	molecular_function	GTPase activity
H	0005515	molecular_function	protein binding
H	0005525	molecular_function	GTP binding
H	0005737	cellular_component	cytoplasm
H	0005886	cellular_component	plasma membrane
H	0006414	biological_process	translational elongation
H	0032045	cellular_component	guanyl-nucleotide exchange factor complex
H	0097216	molecular_function	guanosine tetraphosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 998

Chain	Residue
G	THR25
G	GDP999
G	HOH1002
G	HOH1003
G	HOH1004
G	HOH1006

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG H 998

Chain	Residue
H	HOH2028
H	HOH2029
H	HOH2030
H	HOH2033
H	THR25
H	ASP80
H	GDP1999

---

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE GDP G 999

Chain	Residue
G	VAL20
G	ASP21
G	HIS22
G	GLY23
G	LYS24
G	THR25
G	THR26
G	ASN135
G	LYS136
G	ASP138
G	MET139
G	SER173
G	ALA174
G	LEU175
G	MG998
G	HOH1002
G	HOH1003

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GDP H 1999

Chain	Residue
H	VAL20
H	ASP21
H	HIS22
H	GLY23
H	LYS24
H	THR25
H	THR26
H	ASN135
H	LYS136
H	ASP138
H	SER173
H	ALA174
H	LEU175
H	MG998
H	HOH2029
H	HOH2030
H	HOH2033
H	HOH2034
H	HOH2035

---

Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNapeEKaRGITIntS

Chain	Residue	Details
G	ASP50-SER65

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	388
Details	Domain: {"description":"tr-type G"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Region: {"description":"G1","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Region: {"description":"G2","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Region: {"description":"G3","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Region: {"description":"G4","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Region: {"description":"G5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29546243","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5OPD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"2022614","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"389663","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"6997043","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7021545","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19150849","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24141193","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"8416965","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	28
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	10
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
G	ASP21

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
H	ASP21

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
G	HIS84

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
H	HIS84

---