1D9E
STRUCTURE OF E. COLI KDO8P SYNTHASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046394 | biological_process | carboxylic acid biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046394 | biological_process | carboxylic acid biosynthetic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| C | 0032991 | cellular_component | protein-containing complex |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046394 | biological_process | carboxylic acid biosynthetic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| D | 0032991 | cellular_component | protein-containing complex |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046394 | biological_process | carboxylic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1999 |
| Chain | Residue |
| A | HOH8 |
| A | HOH23 |
| A | HOH61 |
| A | HOH160 |
| A | HOH352 |
| A | PRO1115 |
| A | ALA1116 |
| A | LYS1138 |
| A | ARG1168 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2999 |
| Chain | Residue |
| B | HOH91 |
| B | HOH139 |
| B | PRO2115 |
| B | ALA2116 |
| B | LYS2138 |
| B | ARG2168 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3999 |
| Chain | Residue |
| C | HOH58 |
| C | HOH83 |
| C | HOH85 |
| C | HOH482 |
| C | PRO3115 |
| C | ALA3116 |
| C | LYS3138 |
| C | ARG3168 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 4999 |
| Chain | Residue |
| D | HOH229 |
| D | HOH249 |
| D | HOH255 |
| D | PRO4115 |
| D | ALA4116 |
| D | LYS4138 |
| D | ARG4168 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2888 |
| Chain | Residue |
| A | LYS1130 |
| B | HOH145 |
| B | SER2030 |
| B | ARG2031 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3888 |
| Chain | Residue |
| C | SER3030 |
| C | ARG3031 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1777 |
| Chain | Residue |
| A | HOH336 |
| A | ARG1063 |
| A | SER1064 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2777 |
| Chain | Residue |
| B | ARG2063 |
| B | SER2064 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3777 |
| Chain | Residue |
| C | ARG3063 |
| C | SER3064 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 4777 |
| Chain | Residue |
| D | ARG4063 |
| D | SER4064 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| A | HIS1202 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| B | HIS2202 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| C | HIS3202 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| D | HIS4202 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 614 |
| Chain | Residue | Details |
| A | ASN1026 | electrostatic stabiliser, hydrogen bond donor |
| A | LYS1060 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 614 |
| Chain | Residue | Details |
| B | ASN2026 | electrostatic stabiliser, hydrogen bond donor |
| B | LYS2060 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 614 |
| Chain | Residue | Details |
| C | ASN3026 | electrostatic stabiliser, hydrogen bond donor |
| C | LYS3060 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 614 |
| Chain | Residue | Details |
| D | ASN4026 | electrostatic stabiliser, hydrogen bond donor |
| D | LYS4060 | electrostatic stabiliser, hydrogen bond donor |
