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1D4V

Crystal structure of trail-DR5 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0045569molecular_functionTRAIL binding
B0005164molecular_functiontumor necrosis factor receptor binding
B0006955biological_processimmune response
B0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00251
Number of Residues17
DetailsTHD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvIHeKGFYYIysQTyF
ChainResidueDetails
BLEU174-PHE190

site_idPS00652
Number of Residues41
DetailsTNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ckygqd.Ysthwndllf.ClrCtr.Cdsgevelsp..Ctttr..NTVC
ChainResidueDetails
ACYS97-CYS137
ACYS137-CYS178

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:10549288, ECO:0000269|PubMed:26457518, ECO:0007744|PDB:5CIR
ChainResidueDetails
BCYS230

227111

PDB entries from 2024-11-06

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