1D3B

CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000387	biological_process	spliceosomal snRNP assembly
A	0003723	molecular_function	RNA binding
A	0005681	cellular_component	spliceosomal complex
A	0006396	biological_process	RNA processing
B	0003723	molecular_function	RNA binding
C	0000387	biological_process	spliceosomal snRNP assembly
C	0003723	molecular_function	RNA binding
C	0005681	cellular_component	spliceosomal complex
C	0006396	biological_process	RNA processing
D	0003723	molecular_function	RNA binding
E	0000387	biological_process	spliceosomal snRNP assembly
E	0003723	molecular_function	RNA binding
E	0005681	cellular_component	spliceosomal complex
E	0006396	biological_process	RNA processing
F	0003723	molecular_function	RNA binding
G	0000387	biological_process	spliceosomal snRNP assembly
G	0003723	molecular_function	RNA binding
G	0005681	cellular_component	spliceosomal complex
G	0006396	biological_process	RNA processing
H	0003723	molecular_function	RNA binding
I	0000387	biological_process	spliceosomal snRNP assembly
I	0003723	molecular_function	RNA binding
I	0005681	cellular_component	spliceosomal complex
I	0006396	biological_process	RNA processing
J	0003723	molecular_function	RNA binding
K	0000387	biological_process	spliceosomal snRNP assembly
K	0003723	molecular_function	RNA binding
K	0005681	cellular_component	spliceosomal complex
K	0006396	biological_process	RNA processing
L	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CIT G 701

Chain	Residue
G	ASN23
G	THR24
G	GLY25
G	ARG51
G	ARG69
G	HOH713
G	HOH714
H	ARG25
H	ARG49

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT B 702

Chain	Residue
B	SER7
B	MET9
B	MET38
B	LEU77
B	VAL78
B	SER79
B	MET80
B	HOH714
B	HOH715
B	HOH718
C	GLN42
C	GLN60

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CIT I 703

Chain	Residue
I	GLU21
I	ASN23
I	THR24
I	GLY25
I	ARG69
I	HOH724
I	HOH732
I	HOH733
J	ARG25
J	ARG49

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 601

Chain	Residue
H	ASP23
H	ARG49
H	HOH604
H	HOH605
H	HOH622
H	HOH645

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL I 602

Chain	Residue
I	ILE17
I	VAL18
I	THR19
I	ARG29
I	ILE72
I	LEU73
I	PRO74

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL G 603

Chain	Residue
G	ASN23
G	ARG69
G	HOH743
H	LEU21
H	GLN22
H	ASP23
H	ASN76

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 604

Chain	Residue
D	THR2
D	HIS12
D	MET17
D	MET80
D	HOH624
D	HOH638

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL L 605

Chain	Residue
L	ARG18
L	ILE28
L	GLU62

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL C 606

Chain	Residue
B	GOL611
C	ARG51
C	ASP52

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 607

Chain	Residue
A	THR47
A	THR49
A	VAL55
L	ARG16
L	HOH611
L	HOH653

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 608

Chain	Residue
A	ASN23
A	ARG69
B	GLN22
B	ASP23
B	ASN76
C	HOH614

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL F 609

Chain	Residue
F	ARG18
F	ILE26
F	PHE48
F	GLU62
F	GOL613
F	HOH658

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 610

Chain	Residue
E	ASN23
E	ARG69
F	GLN22
F	ASP23
F	ASN76

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 611

Chain	Residue
B	ASP23
B	ARG25
B	ARG49
B	ILE51
B	HOH727
C	ASP52
C	GOL606

---

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL E 612

Chain	Residue
F	HOH624
F	HOH654
F	HOH664
E	GLU21
E	GLY25
E	ARG69
E	HOH613
F	ARG25
F	ARG49

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL F 613

Chain	Residue
F	PHE48
F	GLU62
F	LYS64
F	GOL609
J	ARG61
J	GLU63

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 614

Chain	Residue
A	ILE17
A	THR19
A	ILE72
A	PRO74

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:19413330

Chain	Residue	Details
A	SER2
C	SER2
E	SER2
G	SER2
I	SER2
K	SER2

---