Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | CBP10 |
| A | HIS201 |
| A | HIS205 |
| A | HIS211 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | CBP11 |
| B | HIS501 |
| B | HIS505 |
| B | HIS511 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 3 |
| Chain | Residue |
| A | ASP153 |
| A | HIS166 |
| A | HIS179 |
| A | HIS151 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 4 |
| Chain | Residue |
| B | HIS451 |
| B | ASP453 |
| B | HIS466 |
| B | HIS479 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 5 |
| Chain | Residue |
| A | TRP92 |
| A | ASP141 |
| A | GLY171 |
| A | ASN173 |
| A | GLY175 |
| A | HOH665 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 6 |
| Chain | Residue |
| B | ASP441 |
| B | ASN473 |
| B | GLY475 |
| B | ASP477 |
| B | HOH664 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 7 |
| Chain | Residue |
| A | ASP158 |
| A | GLY159 |
| A | SER161 |
| A | LEU163 |
| A | ASP181 |
| A | GLU184 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 8 |
| Chain | Residue |
| B | ASP458 |
| B | GLY459 |
| B | SER461 |
| B | LEU463 |
| B | ASP481 |
| B | GLU484 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CBP A 10 |
| Chain | Residue |
| A | ZN1 |
| A | TYR155 |
| A | LEU163 |
| A | LEU164 |
| A | ALA165 |
| A | ILE197 |
| A | HIS201 |
| A | GLU202 |
| A | HIS205 |
| A | HIS211 |
| A | LEU218 |
| A | PHE220 |
| A | PRO221 |
| A | ILE222 |
| A | TYR223 |
| A | THR224 |
| A | HOH604 |
| A | HOH773 |
| A | HOH849 |
| site_id | BC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE CBP B 11 |
| Chain | Residue |
| B | ZN2 |
| B | LEU463 |
| B | LEU464 |
| B | ALA465 |
| B | ILE497 |
| B | HIS501 |
| B | GLU502 |
| B | HIS505 |
| B | HIS511 |
| B | LEU518 |
| B | PHE520 |
| B | PRO521 |
| B | ILE522 |
| B | TYR523 |
| B | THR524 |
| B | HOH738 |
| B | HOH759 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHELGHSL |
| Chain | Residue | Details |
| A | VAL198-LEU207 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU202 | |
| B | GLU502 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP107 | |
| B | MET519 | |
| A | ASN173 | |
| A | ASP177 | |
| A | ASP182 | |
| A | MET219 | |
| B | ASP407 | |
| B | ASN473 | |
| B | ASP477 | |
| B | ASP482 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP141 | |
| B | ASP458 | |
| B | GLY459 | |
| B | SER461 | |
| B | LEU463 | |
| B | GLY475 | |
| B | ASP481 | |
| B | GLU484 | |
| A | ASP158 | |
| A | GLY159 | |
| A | SER161 | |
| A | LEU163 | |
| A | GLY175 | |
| A | ASP181 | |
| A | GLU184 | |
| B | ASP441 | |
| Chain | Residue | Details |
| A | HIS151 | |
| B | HIS466 | |
| B | HIS479 | |
| B | HIS501 | |
| B | HIS505 | |
| B | HIS511 | |
| A | ASP153 | |
| A | HIS166 | |
| A | HIS179 | |
| A | HIS201 | |
| A | HIS205 | |
| A | HIS211 | |
| B | HIS451 | |
| B | ASP453 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN96 | |
| A | ASN131 | |
| B | ASN396 | |
| B | ASN431 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | MET219 | |
| A | GLU202 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | MET519 | |
| B | GLU502 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU202 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLU502 | |
