1CWD

HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHOPEPTIDE

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR CHAIN P OF (PHOSPHONOMETHYL)PHENYLALANINE-CONTAINING PEPTIDE PRO-GLU- GLY-ASP-PM3-GLU-GLU-VAL-LEU

Chain	Residue
L	ARG12
L	ARG74
L	HIS86
L	ASN89
L	GLY93
L	HOH102
L	HOH111
P	HOH10
P	HOH12
P	HOH15
P	HOH21
L	ARG32
L	SER42
L	LYS57
L	HIS58
L	TYR59
L	LYS60
L	ASP65
L	SER72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
L	GLY53
L	SER40
L	SER72

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
L	THR37

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P06240

Chain	Residue	Details
L	TYR70

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:38225265

Chain	Residue	Details
L	GLN50

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