1CQT
CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| I | 0003677 | molecular_function | DNA binding |
| I | 0070974 | molecular_function | POU domain binding |
| J | 0003677 | molecular_function | DNA binding |
| J | 0070974 | molecular_function | POU domain binding |
Functional Information from PROSITE/UniProt
| site_id | PS00027 |
| Number of Residues | 24 |
| Details | HOMEOBOX_1 'Homeobox' domain signature. IAdqLnMEkeVIRVWFcNrrqkeK |
| Chain | Residue | Details |
| A | ILE134-LYS157 |
| site_id | PS00035 |
| Number of Residues | 13 |
| Details | POU_1 POU-specific (POUs) domain signature 1. RRIkLGFtQgDVG |
| Chain | Residue | Details |
| A | ARG19-GLY31 |
| site_id | PS00465 |
| Number of Residues | 14 |
| Details | POU_2 POU-specific (POUs) domain signature 2. SQTTISRFEaLnLS |
| Chain | Residue | Details |
| A | SER43-SER56 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"1684878","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Domain: {"description":"OCA","evidences":[{"source":"PROSITE-ProRule","id":"PRU01347","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"35576971","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
