Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004769 | molecular_function | steroid delta-isomerase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008203 | biological_process | cholesterol metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016995 | molecular_function | cholesterol oxidase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AND A 508 |
| Chain | Residue |
| A | GLN75 |
| A | FAD510 |
| A | VAL77 |
| A | PHE83 |
| A | GLY120 |
| A | THR342 |
| A | PRO344 |
| A | ALA363 |
| A | LEU375 |
| A | TYR446 |
| site_id | AC2 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 510 |
| Chain | Residue |
| A | GLY18 |
| A | GLY20 |
| A | TYR21 |
| A | GLY22 |
| A | GLU41 |
| A | MET42 |
| A | TYR107 |
| A | GLY109 |
| A | ARG110 |
| A | GLY111 |
| A | GLY114 |
| A | GLY115 |
| A | VAL118 |
| A | ASN119 |
| A | GLY120 |
| A | GLY121 |
| A | MET122 |
| A | HIS248 |
| A | VAL250 |
| A | ALA288 |
| A | ALA289 |
| A | GLY290 |
| A | TYR446 |
| A | HIS447 |
| A | ASP474 |
| A | GLY475 |
| A | ASN485 |
| A | PRO486 |
| A | PHE487 |
| A | AND508 |
| A | HOH517 |
| A | HOH518 |
| A | HOH524 |
| A | HOH530 |
| A | HOH533 |
| A | HOH535 |
| A | HOH573 |
| A | HOH600 |
Functional Information from PROSITE/UniProt
| site_id | PS00623 |
| Number of Residues | 24 |
| Details | GMC_OXRED_1 GMC oxidoreductases signature 1. GRgVGGGSlVNggmAvtPkrnyfE |
| Chain | Residue | Details |
| A | GLY109-GLU132 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU361 | |
| A | HIS447 | |
| Chain | Residue | Details |
| A | TYR21 | |
| A | GLU41 | |
| A | GLY115 | |
| A | ASN119 | |
| A | VAL250 | |
| A | TYR446 | |
| A | GLY475 | |
| A | PHE487 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | a catalytic site defined by CSA, PubMed 2051487, 1542121, 8218217, 10194345 |
| Chain | Residue | Details |
| A | ASN485 | |
| A | GLU361 | |
| A | HIS447 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 354 |
| Chain | Residue | Details |
| A | GLU361 | proton acceptor, proton donor |
| A | HIS447 | electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN485 | activator, electrostatic stabiliser, increase acidity, increase basicity |
