1CLV
YELLOW MEAL WORM ALPHA-AMYLASE IN COMPLEX WITH THE AMARANTH ALPHA-AMYLASE INHIBITOR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004556 | molecular_function | alpha-amylase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008152 | biological_process | metabolic process |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0031404 | molecular_function | chloride ion binding |
| A | 0043169 | molecular_function | cation binding |
| A | 0046872 | molecular_function | metal ion binding |
| I | 0004866 | molecular_function | endopeptidase inhibitor activity |
| I | 0015066 | molecular_function | alpha-amylase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 601 |
| Chain | Residue |
| A | HOH628 |
| A | ASN98 |
| A | ARG146 |
| A | ASP155 |
| A | HIS189 |
| A | HOH611 |
| A | HOH619 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 602 |
| Chain | Residue |
| A | ARG183 |
| A | LEU243 |
| A | ARG321 |
| site_id | ACS |
| Number of Residues | 3 |
| Details | CATALYTIC SITE |
| Chain | Residue |
| A | ASP185 |
| A | GLU222 |
| A | ASP287 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:9600843 |
| Chain | Residue | Details |
| A | VAL184 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:9600843 |
| Chain | Residue | Details |
| A | GLN221 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10508777, ECO:0000269|PubMed:9600843, ECO:0000269|PubMed:9687373, ECO:0007744|PDB:1JAE |
| Chain | Residue | Details |
| A | ILE97 | |
| A | VAL145 | |
| A | ARG154 | |
| A | PHE182 | |
| A | LYS188 | |
| A | ASP284 | |
| A | THR320 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000250|UniProtKB:P04746 |
| Chain | Residue | Details |
| A | HIS286 |
