1CKN
STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004484 | molecular_function | mRNA guanylyltransferase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005525 | molecular_function | GTP binding |
A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
A | 0006370 | biological_process | 7-methylguanosine mRNA capping |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004484 | molecular_function | mRNA guanylyltransferase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005525 | molecular_function | GTP binding |
B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
B | 0006370 | biological_process | 7-methylguanosine mRNA capping |
B | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MN B 1001 |
Chain | Residue |
B | GPL82 |
B | HOH1114 |
B | HOH1121 |
B | HOH1122 |
B | HOH1156 |
B | HOH1163 |
site_id | AC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 B 1000 |
Chain | Residue |
B | ARG106 |
B | ARG228 |
B | LYS234 |
B | ASP244 |
B | LYS298 |
B | ASN302 |
B | HOH1151 |
B | HOH1154 |
B | HOH1171 |
B | GPL82 |
site_id | AC3 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE GTP A 899 |
Chain | Residue |
A | PRO59 |
A | PRO61 |
A | LYS82 |
A | THR83 |
A | ARG87 |
A | ARG106 |
A | GLU131 |
A | PHE146 |
A | LYS188 |
A | TRP190 |
A | ILE216 |
A | LEU232 |
A | LYS234 |
A | HOH995 |
A | HOH1023 |
A | HOH1032 |
A | HOH1043 |
A | HOH1048 |
A | HOH1050 |
site_id | GMA |
Number of Residues | 1 |
Details | ACTIVE SITE LYSINE. |
Chain | Residue |
A | LYS82 |
site_id | GMB |
Number of Residues | 1 |
Details | ACTIVE SITE LYSINE. |
Chain | Residue |
B | GPL82 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: N6-GMP-lysine intermediate |
Chain | Residue | Details |
B | GPL82 |