1CHP

SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0005515	molecular_function	protein binding
D	0005534	molecular_function	galactose binding
D	0005576	cellular_component	extracellular region
D	0020002	cellular_component	host cell plasma membrane
D	0035821	biological_process	modulation of process of another organism
D	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
D	0042597	cellular_component	periplasmic space
D	0046812	molecular_function	host cell surface binding
D	0090729	molecular_function	toxin activity
D	1902494	cellular_component	catalytic complex
E	0005515	molecular_function	protein binding
E	0005534	molecular_function	galactose binding
E	0005576	cellular_component	extracellular region
E	0020002	cellular_component	host cell plasma membrane
E	0035821	biological_process	modulation of process of another organism
E	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
E	0042597	cellular_component	periplasmic space
E	0046812	molecular_function	host cell surface binding
E	0090729	molecular_function	toxin activity
E	1902494	cellular_component	catalytic complex
F	0005515	molecular_function	protein binding
F	0005534	molecular_function	galactose binding
F	0005576	cellular_component	extracellular region
F	0020002	cellular_component	host cell plasma membrane
F	0035821	biological_process	modulation of process of another organism
F	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
F	0042597	cellular_component	periplasmic space
F	0046812	molecular_function	host cell surface binding
F	0090729	molecular_function	toxin activity
F	1902494	cellular_component	catalytic complex
G	0005515	molecular_function	protein binding
G	0005534	molecular_function	galactose binding
G	0005576	cellular_component	extracellular region
G	0020002	cellular_component	host cell plasma membrane
G	0035821	biological_process	modulation of process of another organism
G	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
G	0042597	cellular_component	periplasmic space
G	0046812	molecular_function	host cell surface binding
G	0090729	molecular_function	toxin activity
G	1902494	cellular_component	catalytic complex
H	0005515	molecular_function	protein binding
H	0005534	molecular_function	galactose binding
H	0005576	cellular_component	extracellular region
H	0020002	cellular_component	host cell plasma membrane
H	0035821	biological_process	modulation of process of another organism
H	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
H	0042597	cellular_component	periplasmic space
H	0046812	molecular_function	host cell surface binding
H	0090729	molecular_function	toxin activity
H	1902494	cellular_component	catalytic complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL H 249

Chain	Residue
D	HIS13
H	TYR12
H	HIS13
H	TRP88
H	HOH255

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