1CHD

CHEB METHYLESTERASE DOMAIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000156	molecular_function	phosphorelay response regulator activity
A	0000160	biological_process	phosphorelay signal transduction system
A	0005737	cellular_component	cytoplasm
A	0006935	biological_process	chemotaxis
A	0008984	molecular_function	protein-glutamate methylesterase activity

Functional Information from PDB Data

site_id	ACT
Number of Residues	3
Details	ACTIVE SITE

Chain	Residue
A	SER164
A	HIS190
A	ASP286

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site_id	OXY
Number of Residues	2
Details	PROPOSED OXYANION HOLE

Chain	Residue
A	MET283
A	THR165

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00099, ECO:0000305|PubMed:7608974

Chain	Residue	Details
A	SER164
A	HIS190
A	ASP286

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	a catalytic site defined by CSA, PubMed 7608974

Chain	Residue	Details
A	SER164
A	HIS190
A	ASP286
A	THR165
A	MET283

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site_id	MCSA1
Number of Residues	5
Details	M-CSA 337

Chain	Residue	Details
A	SER164	activator, covalently attached, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
A	THR165	electrostatic stabiliser, hydrogen bond donor
A	HIS190	activator, electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
A	MET283	electrostatic stabiliser, hydrogen bond donor
A	ASP286	electrostatic stabiliser, hydrogen bond acceptor

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