Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046294 | biological_process | formaldehyde catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051903 | molecular_function | S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046294 | biological_process | formaldehyde catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051903 | molecular_function | S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 376 |
| Chain | Residue |
| A | NAD375 |
| A | HOH1352 |
| A | CYS46 |
| A | HIS68 |
| A | CYS175 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 377 |
| Chain | Residue |
| A | CYS98 |
| A | CYS101 |
| A | CYS104 |
| A | CYS112 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 376 |
| Chain | Residue |
| B | CYS46 |
| B | HIS68 |
| B | CYS175 |
| B | NAD375 |
| B | HOH1253 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 377 |
| Chain | Residue |
| B | CYS98 |
| B | CYS101 |
| B | CYS104 |
| B | CYS112 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAD A 375 |
| Chain | Residue |
| A | HIS47 |
| A | THR48 |
| A | CYS175 |
| A | THR179 |
| A | GLY200 |
| A | GLY202 |
| A | ALA203 |
| A | VAL204 |
| A | VAL223 |
| A | ASP224 |
| A | LEU225 |
| A | LYS229 |
| A | CYS269 |
| A | VAL270 |
| A | GLY271 |
| A | VAL275 |
| A | VAL293 |
| A | TRP295 |
| A | SER317 |
| A | PHE319 |
| A | ARG369 |
| A | ZN376 |
| A | HOH849 |
| A | HOH952 |
| A | HOH1010 |
| A | HOH1213 |
| A | HOH1256 |
| A | HOH1257 |
| site_id | AC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD B 375 |
| Chain | Residue |
| B | HIS47 |
| B | THR179 |
| B | GLY200 |
| B | GLY202 |
| B | ALA203 |
| B | VAL204 |
| B | ASP224 |
| B | LEU225 |
| B | LYS229 |
| B | CYS269 |
| B | VAL270 |
| B | VAL275 |
| B | VAL293 |
| B | GLY294 |
| B | TRP295 |
| B | SER317 |
| B | MET318 |
| B | PHE319 |
| B | ARG369 |
| B | ZN376 |
| B | HOH857 |
| B | HOH859 |
| B | HOH863 |
| B | HOH1117 |
| B | HOH1240 |
| B | HOH1253 |
| B | HOH1259 |
| B | HOH1341 |
| B | HOH1357 |
| B | HOH1385 |
| site_id | ZIN |
| Number of Residues | 6 |
| Details | |
| Chain | Residue |
| A | CYS46 |
| A | GLY174 |
| A | GLY67 |
| B | CYS46 |
| B | GLY174 |
| B | GLY67 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEgAGIvesvGpgV |
| Chain | Residue | Details |
| A | GLY67-VAL81 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"1567829","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | THR48 | |
| A | HIS47 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | THR48 | |
| B | HIS47 | |
