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1CD9

2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR

Functional Information from GO Data
ChainGOidnamespacecontents
A0005102molecular_functionsignaling receptor binding
A0005125molecular_functioncytokine activity
A0005130molecular_functiongranulocyte colony-stimulating factor receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006955biological_processimmune response
A0008083molecular_functiongrowth factor activity
A0008284biological_processpositive regulation of cell population proliferation
A0019221biological_processcytokine-mediated signaling pathway
A0019899molecular_functionenzyme binding
A0030838biological_processpositive regulation of actin filament polymerization
A0030851biological_processgranulocyte differentiation
A0038158biological_processgranulocyte colony-stimulating factor signaling pathway
A0043202cellular_componentlysosomal lumen
A0045471biological_processresponse to ethanol
A0045639biological_processpositive regulation of myeloid cell differentiation
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0050731biological_processpositive regulation of peptidyl-tyrosine phosphorylation
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0071222biological_processcellular response to lipopolysaccharide
A0071345biological_processcellular response to cytokine stimulus
A0071682cellular_componentendocytic vesicle lumen
A0110053biological_processregulation of actin filament organization
C0005102molecular_functionsignaling receptor binding
C0005125molecular_functioncytokine activity
C0005130molecular_functiongranulocyte colony-stimulating factor receptor binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0006955biological_processimmune response
C0008083molecular_functiongrowth factor activity
C0008284biological_processpositive regulation of cell population proliferation
C0019221biological_processcytokine-mediated signaling pathway
C0019899molecular_functionenzyme binding
C0030838biological_processpositive regulation of actin filament polymerization
C0030851biological_processgranulocyte differentiation
C0038158biological_processgranulocyte colony-stimulating factor signaling pathway
C0043202cellular_componentlysosomal lumen
C0045471biological_processresponse to ethanol
C0045639biological_processpositive regulation of myeloid cell differentiation
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0050731biological_processpositive regulation of peptidyl-tyrosine phosphorylation
C0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C0071222biological_processcellular response to lipopolysaccharide
C0071345biological_processcellular response to cytokine stimulus
C0071682cellular_componentendocytic vesicle lumen
C0110053biological_processregulation of actin filament organization
Functional Information from PROSITE/UniProt
site_idPS00254
Number of Residues26
DetailsINTERLEUKIN_6 Interleukin-6 / G-CSF / MGF signature. CpsqalqlagClsqlhsGLflYqglL
ChainResidueDetails
ACYS65-LEU90

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10537111
ChainResidueDetails
BASN10
DASN10

site_idSWS_FT_FI2
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN67
BASN160
DASN67
DASN160

218853

PDB entries from 2024-04-24

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