1CBU

ADENOSYLCOBINAMIDE KINASE/ADENOSYLCOBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE (COBU) FROM SALMONELLA TYPHIMURIUM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005525	molecular_function	GTP binding
A	0008820	molecular_function	cobinamide phosphate guanylyltransferase activity
A	0009236	biological_process	cobalamin biosynthetic process
A	0016301	molecular_function	kinase activity
A	0036428	molecular_function	adenosylcobinamide kinase (GTP-specific) activity
A	0036429	molecular_function	adenosylcobinamide kinase (ATP-specific) activity
A	0043752	molecular_function	adenosylcobinamide kinase activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005525	molecular_function	GTP binding
B	0008820	molecular_function	cobinamide phosphate guanylyltransferase activity
B	0009236	biological_process	cobalamin biosynthetic process
B	0016301	molecular_function	kinase activity
B	0036428	molecular_function	adenosylcobinamide kinase (GTP-specific) activity
B	0036429	molecular_function	adenosylcobinamide kinase (ATP-specific) activity
B	0043752	molecular_function	adenosylcobinamide kinase activity
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005525	molecular_function	GTP binding
C	0008820	molecular_function	cobinamide phosphate guanylyltransferase activity
C	0009236	biological_process	cobalamin biosynthetic process
C	0016301	molecular_function	kinase activity
C	0036428	molecular_function	adenosylcobinamide kinase (GTP-specific) activity
C	0036429	molecular_function	adenosylcobinamide kinase (ATP-specific) activity
C	0043752	molecular_function	adenosylcobinamide kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 801

Chain	Residue
A	ARG9
A	SER10
A	GLY11
A	LYS12
A	SER13
A	HOH692
C	GLN559

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 802

Chain	Residue
B	SER210
B	GLY211
B	LYS212
B	SER213
A	HOH783
B	ARG209

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 803

Chain	Residue
B	HOH648
C	ARG409
C	SER410
C	GLY411
C	LYS412
C	SER413

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: GMP-histidine intermediate => ECO:0000269|PubMed:10529169

Chain	Residue	Details
A	HIS46
B	HIS246
C	HIS446

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site_id	SWS_FT_FI2
Number of Residues	15
Details	BINDING:

Chain	Residue	Details
A	GLY6
B	GLU280
C	GLY406
C	ALA430
C	LYS447
C	GLU458
C	GLU480
A	ALA30
A	LYS47
A	GLU58
A	GLU80
B	GLY206
B	ALA230
B	LYS247
B	GLU258

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