1C8S

BACTERIORHODOPSIN D96N LATE M STATE INTERMEDIATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE LI1 A 601

Chain	Residue
A	ILE11
A	LI1612
A	SQU701
A	PHE54
A	LEU58
A	LEU62
A	VAL136
A	ILE140
A	ALA143
A	LI1606
A	LI1608

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LI1 A 602

Chain	Residue
A	TRP12
A	TYR131
A	PHE135
A	TRP138
A	ALA139
A	ALA196
A	LI1603
A	LI1608

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LI1 A 603

Chain	Residue
A	LEU190
A	ALA196
A	VAL199
A	PRO200
A	LI1602
A	LI1610

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE LI1 A 605

Chain	Residue
A	ALA18
A	LEU22
A	LI1606

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LI1 A 606

Chain	Residue
A	THR17
A	ALA18
A	LEU22
A	LI1601
A	LI1605

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE LI1 A 607

Chain	Residue
A	ILE52
A	MET56
A	TYR64
A	TRP80
A	TRP80
A	LEU87
A	GLY116
A	ILE117
A	VAL124
A	LEU127

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LI1 A 608

Chain	Residue
A	ILE222
A	LI1601
A	LI1602
A	SQU701

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE LI1 A 609

Chain	Residue
A	VAL177
A	LI1610

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE LI1 A 610

Chain	Residue
A	ASN176
A	VAL179
A	VAL180
A	SER183
A	ALA184
A	VAL187
A	LI1603
A	LI1609

---

site_id	BC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE LI1 A 612

Chain	Residue
A	GLY21
A	THR24
A	LEU28
A	ALA44
A	THR47
A	LEU48
A	ALA51
A	PHE54
A	ALA110
A	ILE117
A	ALA144
A	TYR147
A	LI1601

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE LI1 A 613

Chain	Residue
A	LEU87
A	LEU95

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SQU A 701

Chain	Residue
A	LEU25
A	TYR26
A	SER214
A	LEU221
A	LI1601
A	LI1608

---

site_id	BC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE RET A 301

Chain	Residue
A	TRP86
A	THR90
A	LEU93
A	GLY122
A	TRP138
A	SER141
A	TRP182
A	TYR185
A	ASP212
A	ALA215
A	LYS216

---

Functional Information from PROSITE/UniProt

site_id	PS00327
Number of Residues	12
Details	BACTERIAL_OPSIN_RET Bacterial rhodopsins retinal binding site. FMVLDVsAKvGF

Chain	Residue	Details
A	PHE208-PHE219

---

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYaDWlFTTPLLL

Chain	Residue	Details
A	ARG82-LEU94

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	ALA14-LEU22
A	ASN76-LEU92
A	SER141-TYR147

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix A => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	GLY23-PHE42

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	TYR43-MET56
A	ALA110-GLY120
A	LEU190-LEU207

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	TRANSMEM: Helical; Name=Helix B => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	TYR57-GLN75

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	TRANSMEM: Helical; Name=Helix C => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	LEU93-LEU109

---

site_id	SWS_FT_FI6
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix D => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	THR121-ILE140

---

site_id	SWS_FT_FI7
Number of Residues	19
Details	TRANSMEM: Helical; Name=Helix E => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain	Residue	Details
A	ILE148-TRP189

---

site_id	SWS_FT_FI8
Number of Residues	18
Details	TRANSMEM: Helical; Name=Helix F => ECO:0000269|PubMed:10452895, ECO:0000269|PubMed:28008064, ECO:0007744|PDB:1C3W

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	SITE: Primary proton acceptor => ECO:0000305|PubMed:10903866, ECO:0000305|PubMed:10949309, ECO:0000305|PubMed:28008064

Chain	Residue	Details
A	ALA98

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:9541408

Chain	Residue	Details
A	ALA14

---