1C4X

2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE (BPHD) FROM RHODOCOCCUS SP. STRAIN RHA1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	a catalytic site defined by CSA, PubMed 11399084

Chain	Residue	Details
A	HIS263
A	SER110
A	ASP235

---

site_id	MCSA1
Number of Residues	8
Details	M-CSA 437

Chain	Residue	Details
A	GLY40	electrostatic stabiliser
A	ASN109	electrostatic stabiliser
A	SER110	covalent catalysis, electrostatic stabiliser, proton shuttle (general acid/base)
A	MET111	electrostatic stabiliser
A	ARG186	electrostatic destabiliser, steric role
A	ASP235	modifies pKa
A	HIS263	proton shuttle (general acid/base)
A	TRP264	electrostatic stabiliser

---