1BY3

FHUA FROM E. COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0009279	cellular_component	cell outer membrane
A	0015343	molecular_function	siderophore-iron transmembrane transporter activity
A	0015344	molecular_function	siderophore uptake transmembrane transporter activity
A	0015643	molecular_function	toxic substance binding
A	0015891	biological_process	siderophore transport
A	0016020	cellular_component	membrane
A	0019904	molecular_function	protein domain specific binding
A	0033214	biological_process	siderophore-iron import into cell
A	0038023	molecular_function	signaling receptor activity
A	0044718	biological_process	siderophore transmembrane transport
A	0046790	molecular_function	virion binding
A	1902495	cellular_component	transmembrane transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE OES A 715

Chain	Residue
A	THR176
A	SER200
A	PHE290
A	ASN291
A	PHE294

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE OES A 716

Chain	Residue
A	TYR284
A	GLN298
A	VAL676
A	ALA710

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OES A 717

Chain	Residue
A	PHE302
A	PHE355
A	VAL669

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE OES A 718

Chain	Residue
A	TYR116
A	TRP246
A	GLN309
A	SER311
A	TYR313

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE OES A 719

Chain	Residue
A	TYR213

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OES A 720

Chain	Residue
A	ALA214
A	ILE215
A	PHE235

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OES A 721

Chain	Residue
A	VAL164
A	TRP455
A	ASP457
A	ASP472
A	PHE714
A	HOH1072

---

Functional Information from PROSITE/UniProt

site_id	PS01156
Number of Residues	18
Details	TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. GcfwGaERqVvATAtFrF

Chain	Residue	Details
A	GLY697-PHE714

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	204
Details	TOPO_DOM: Periplasmic

Chain	Residue	Details
A	ALA1-GLU159
A	PHE622-SER628
A	LEU666-ALA672
A	PHE714
A	SER183-VAL189
A	PRO223-LYS226
A	GLU289-THR293
A	LYS364-ASP371
A	GLN441-LYS444
A	LEU485-GLY489
A	VAL528-ARG532
A	LEU578-ALA580

---

site_id	SWS_FT_FI2
Number of Residues	177
Details	TRANSMEM: Beta stranded

Chain	Residue	Details
A	PRO160-ALA168
A	THR432-ALA440
A	VAL445-TYR453
A	PHE476-TYR484
A	VAL490-GLU498
A	LYS519-TYR527
A	PRO533-TYR541
A	GLY569-PRO577
A	SER581-THR589
A	MET613-THR621
A	GLY629-ARG637
A	PHE174-ASP182
A	VAL657-ASP665
A	GLY673-ASN681
A	GLN705-ARG713
A	TYR190-ALA198
A	TYR213-ARG222
A	THR227-PHE235
A	LYS280-HIS288
A	PHE294-PHE302
A	PHE355-SER363
A	HIS372-PHE380

---

site_id	SWS_FT_FI3
Number of Residues	289
Details	TOPO_DOM: Extracellular

Chain	Residue	Details
A	GLY169-LEU173
A	TYR638-THR656
A	ASN682-ARG704
A	ARG199-ARG212
A	GLN236-GLU279
A	ALA303-ASN354
A	MET381-GLN431
A	ASP454-GLN475
A	SER499-GLY518
A	ASN542-ARG568
A	TYR590-HIS612

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	BINDING: BINDING => ECO:0000305|PubMed:10850805, ECO:0000305|PubMed:9856937, ECO:0000305|PubMed:9865695

Chain	Residue	Details
A	ARG81
A	GLN100
A	PHE115
A	TYR244
A	TYR313

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305|PubMed:9856937

Chain	Residue	Details
A	PHE391
A	ALA702

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	SITE: Interaction with phage T5 RBP-pb5 => ECO:0000269|PubMed:36779755

Chain	Residue	Details
A	PRO533

---